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A quantitative review of heterozygosity–fitness correlations in animal populations
The ease of obtaining genotypic data from wild populations has renewed interest in the
relationship between individual genetic diversity and fitness‐related traits (heterozygosity …
relationship between individual genetic diversity and fitness‐related traits (heterozygosity …
Assessment of identity disequilibrium and its relation to empirical heterozygosity fitness correlations: a meta‐analysis
Heterozygosity fitness correlations (HFC s) have frequently been used to detect inbreeding
depression, under the assumption that genome‐wide heterozygosity is a good proxy for …
depression, under the assumption that genome‐wide heterozygosity is a good proxy for …
Multi-generational benefits of genetic rescue
DP Onorato, MW Cunningham, M Lotz, M Criffield… - Scientific Reports, 2024 - nature.com
Genetic rescue—an increase in population fitness following the introduction of new alleles—
has been proven to ameliorate inbreeding depression in small, isolated populations, yet is …
has been proven to ameliorate inbreeding depression in small, isolated populations, yet is …
Conservation genetics of population bottlenecks: the role of chance, selection, and history
JL Bouzat - Conservation Genetics, 2010 - Springer
Conservation genetics studies of populations bottlenecks are commonly framed under the
detrimental paradigm of inbreeding depression. This conceptual paradigm presupposes a …
detrimental paradigm of inbreeding depression. This conceptual paradigm presupposes a …
From reference genomes to population genomics: comparing three reference-aligned reduced-representation sequencing pipelines in two wildlife species
Background Recent advances in genomics have greatly increased research opportunities
for non-model species. For wildlife, a growing availability of reference genomes means that …
for non-model species. For wildlife, a growing availability of reference genomes means that …
Estimating genome-wide heterozygosity: effects of demographic history and marker type
Heterozygosity–fitness correlations (HFCs) are often used to link individual genetic variation
to differences in fitness. However, most studies examining HFCs find weak or no …
to differences in fitness. However, most studies examining HFCs find weak or no …
Specific alleles at immune genes, rather than genome‐wide heterozygosity, are related to immunity and survival in the critically endangered Attwater's prairie‐chicken
ZW Bateson, SC Hammerly, JA Johnson… - Molecular …, 2016 - Wiley Online Library
The negative effects of inbreeding on fitness are serious concerns for populations of
endangered species. Reduced fitness has been associated with lower genome‐wide …
endangered species. Reduced fitness has been associated with lower genome‐wide …
Reduced heterozygosity impairs sperm quality in endangered mammals
Inbreeding causes increases in homozygosity and is commonly associated with reductions
in fertility and embryogenesis. Although the mechanisms underlying such effects are …
in fertility and embryogenesis. Although the mechanisms underlying such effects are …
A dominance hypothesis argument for historical genetic gains and the fixation of heterosis in octoploid strawberry
Heterosis was the catalyst for the domestication of cultivated strawberry (F ragaria×
ananassa), an interspecific hybrid species that originated in the 1700s. The hybrid origin …
ananassa), an interspecific hybrid species that originated in the 1700s. The hybrid origin …
Conservation planning for adaptive and neutral evolutionary processes
Protected area systems should ideally maintain adaptive and neutral evolutionary
processes. To achieve this, plans for expanding protected area systems (prioritizations) can …
processes. To achieve this, plans for expanding protected area systems (prioritizations) can …