Adverse events in early life can modulate the response to additional stressors later in life
and increase the risk of develo** psychiatric disorders. The underlying molecular …

Exposure to adversities during early life stages (early life adversities-ELA), ranging from
pregnancy to adolescence, represents a major risk factor for the vulnerability to mental …

Social stress is the most significant source of chronic stress in humans and is commonly
associated with health impairment. Individual differences in the behavioral co** …

Background Depression is a neuropsychiatric disease with a high disability rate and mainly
caused by the chronic stress or genetic factors. There is increasing evidence that …

Social stress exposure heightens the risk of substance abuse disorder development,
especially when endured during adolescence, influencing long-term mental health. This …

Stress is a critical factor in the development of mood and drug use disorders. The social
defeat model is not appropriate for female rodents due to their low level of aggression …

Evidence indicates that chronic social stress plays a significant role in the development of
cancer and depression. Although their association is recognized, the precise physiological …

This study investigated the risk to social behavior and cognitive flexibility induced by chronic
social defeat stress (CSDS) during early and late adolescence (EA and LA). Utilizing the …

Background Exposure to intermittent repeated social defeat (IRSD) increases the sensitivity
of mice to the rewarding effects of cocaine in the conditioned place preference (CPP) …

Nicotine has been used during pregnancy and lactation as a tobacco harm reduction
strategy. However, it is unclear whether nicotine exposure during a critical development …