Tackling drug resistance and other causes of treatment failure in leishmaniasis
Leishmaniasis is a tropical infectious disease caused by the protozoan Leishmania parasite.
The disease is transmitted by female sand flies and, depending on the infecting parasite …
The disease is transmitted by female sand flies and, depending on the infecting parasite …
Immunotherapy and immunochemotherapy in combating visceral leishmaniasis
Visceral leishmaniasis (VL), a vector-borne disease, is caused by an obligate
intramacrophage, kinetoplastid protozoan parasite of the genus Leishmania. Globally, VL is …
intramacrophage, kinetoplastid protozoan parasite of the genus Leishmania. Globally, VL is …
[HTML][HTML] Multifunctional, TNF-α and IFN-γ-Secreting CD4 and CD8 T Cells and CD8High T Cells Are Associated With the Cure of Human Visceral Leishmaniasis
LS Rodrigues, AS Barreto, LGS Bomfim… - Frontiers in …, 2021 - frontiersin.org
Visceral leishmaniasis (VL) is a chronic and often fatal disease caused by protozoans of the
genus Leishmania that affects millions of people worldwide. Patients with symptomatic VL …
genus Leishmania that affects millions of people worldwide. Patients with symptomatic VL …
A recombinant chimeric protein-based vaccine containing T-cell epitopes from amastigote proteins and combined with distinct adjuvants, induces immunogenicity and …
DP Lage, DL Vale, FP Linhares, CS Freitas… - Vaccines, 2022 - mdpi.com
Currently, there is no licensed vaccine to protect against human visceral leishmaniasis (VL),
a potentially fatal disease caused by infection with Leishmania parasites. In the current …
a potentially fatal disease caused by infection with Leishmania parasites. In the current …
[HTML][HTML] Inhibitory effect of Eimeria maxima IFN-γ inhibitory molecules on the immune function of T cell subsets in chickens
X Pu, Y Pan, Q **ang, M Lu, L Xu, R Yan, X Li, X Song - Poultry Science, 2023 - Elsevier
It has been reported that infection of chicken coccidian could inhibit the production of Th1
cytokine IFN-γ, thereby evading clearance by the host immune system. The present study …
cytokine IFN-γ, thereby evading clearance by the host immune system. The present study …
Recent advances in the development of adenovirus-vectored vaccines for parasitic infections
Vaccines against parasites have lagged centuries behind those against viral and bacterial
infections, despite the devastating morbidity and widespread effects of parasitic diseases …
infections, despite the devastating morbidity and widespread effects of parasitic diseases …
Exploring the paradox of defense between host and Leishmania parasite
Leishmaniasis, a neglected tropical disease, still remains a global concern for the
healthcare sector. The primary causative agents of the disease comprise diverse …
healthcare sector. The primary causative agents of the disease comprise diverse …
Role of Treg, Breg and other cytokine sets in host protection and immunopathology during human leishmaniasis: Are they potential valuable markers in clinical …
F Divenuto, G Pavia, N Marascio, GS Barreca… - Acta Tropica, 2023 - Elsevier
Leishmaniasis is a vector-borne disease caused by obligate intracellular protozoan
parasites that can infect humans and other mammals. Pro-and anti-inflammatory cytokines …
parasites that can infect humans and other mammals. Pro-and anti-inflammatory cytokines …
CD4+ Th1 and Th17 responses and multifunctional CD8 T lymphocytes associated with cure or disease worsening in human visceral leishmaniasis
MNF de Franca, LS Rodrigues, AS Barreto… - Frontiers in …, 2024 - frontiersin.org
Introduction In VL, a proinflammatory phenotype is typically associated with enhanced
phagocytosis and a Th1 mediated immune response resulting in infection control. In …
phagocytosis and a Th1 mediated immune response resulting in infection control. In …
Metabolic Pathways of Leishmania Parasite: Source of Pertinent Drug Targets and Potent Drug Candidates
Leishmaniasis is a tropical disease caused by a protozoan parasite Leishmania that is
transmitted via infected female sandflies. At present, leishmaniasis treatment mainly counts …
transmitted via infected female sandflies. At present, leishmaniasis treatment mainly counts …