The search for novel, less invasive therapeutic strategies to treat neurodegenerative
diseases has stimulated scientists to investigate the mechanisms involved in …

Monosodium glutamate (MSG) subcutaneously administrated to neonatal rats induces
several neurochemical alterations in the brain, which have been associated with an …

This review assesses many of the health implications and toxicity associated with
monosodium glutamate (MSG) in animal models. MSG is the sodium salt of the amino acid …

Excitotoxicity is a pathological process in which neuronal dysfunction and death are induced
by excessive glutamate stimulation, the major fast excitatory neurotransmitter in the …

NMDA and AMPA receptors are thought to be responsible for Ca++ influx during glutamate-
induced excitotoxicity and, therefore, hippocampal neuronal death. We assessed whether …

Abstract Excessive Glutamate (Glu) release may trigger excitotoxic cellular death by the
activation of intracellular signaling pathways that transduce extracellular signals to the cell …

Monosodium glutamate (MSG) administered to neonatal rats during the first week of life
induces a neurodegenerative process, which is represented by several neurochemical …

Neonatal handling, an experimental model of early life experiences, is known to affect the
hypothalamic–pituitary–adrenal axis function thus increasing adaptability, co** with …

In vitro and in vivo experimental evidence has contributed important knowledge regarding
the antiapoptotic effect mediated by EPO signaling in the damaged brain, particularly …

Vascular endothelial growth factor (VEGF) exerts both neuroprotective and proinflammatory
effects in the brain, depending on the VEGF (A–E) and VEGF receptor (VEGFR1–3) types …