Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

Objective To update the 1995 American Academy of Neurology (AAN) practice parameter on
persistent vegetative state and the 2002 case definition on minimally conscious state (MCS) …

Background Patients with brain injury who are unresponsive to commands may perform
cognitive tasks that are detected on functional magnetic resonance imaging (fMRI) and …

Background and purpose Patients with acquired brain injury and acute or prolonged
disorders of consciousness (DoC) are challenging. Evidence to support diagnostic decisions …

The Glasgow Outcome Scale-Extended (GOSE) has become one of the most widely used
outcome instruments to assess global disability and recovery after traumatic brain injury …

Consciousness can be defined by two components: arousal (wakefulness) and awareness
(subjective experience). However, neurophysiological consciousness metrics able to …

Background Brain activation in response to spoken motor commands can be detected by
electroencephalography (EEG) in clinically unresponsive patients. The prevalence and …

Adopting the framework of brain dynamics as a cornerstone of human consciousness, we
determined whether dynamic signal coordination provides specific and generalizable …

There have been a number of advances in the search for the neural correlates of
consciousness—the minimum neural mechanisms sufficient for any one specific conscious …

The management of patients with severe brain injuries and prolonged disorders of
consciousness raises important issues particularly with respect to their therapeutic options …