Dopamine and addiction
RA Wise, MA Robble - Annual review of psychology, 2020 - annualreviews.org
Addiction is commonly identified with habitual nonmedical self-administration of drugs. It is
usually defined by characteristics of intoxication or by characteristics of withdrawal …
usually defined by characteristics of intoxication or by characteristics of withdrawal …
Behavioral and neurobiological mechanisms of pavlovian and instrumental extinction learning
This article reviews the behavioral neuroscience of extinction, the phenomenon in which a
behavior that has been acquired through Pavlovian or instrumental (operant) learning …
behavior that has been acquired through Pavlovian or instrumental (operant) learning …
Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion
Deficits in decoding rewarding (and aversive) signals are present in several
neuropsychiatric conditions such as depression and addiction, emphasising the importance …
neuropsychiatric conditions such as depression and addiction, emphasising the importance …
Optogenetic investigation of neural circuits underlying brain disease in animal models
Optogenetic tools have provided a new way to establish causal relationships between brain
activity and behaviour in health and disease. Although no animal model captures human …
activity and behaviour in health and disease. Although no animal model captures human …
Multiple reward signals in the brain
W Schultz - Nature reviews neuroscience, 2000 - nature.com
The fundamental biological importance of rewards has created an increasing interest in the
neuronal processing of reward information. The suggestion that the mechanisms underlying …
neuronal processing of reward information. The suggestion that the mechanisms underlying …
Neurobehavioural mechanisms of reward and motivation
The analysis of the behavioural and neural mechanisms of reinforcement and motivation
has benefited from the recent application of learning theory and better anatomical …
has benefited from the recent application of learning theory and better anatomical …
Dopamine neurons and their role in reward mechanisms
W Schultz - Current opinion in neurobiology, 1997 - Elsevier
Information related to rewards is processed by a limited number of brain structures. Recent
studies have demonstrated that dopamine neurons respond to appetitive events, such as …
studies have demonstrated that dopamine neurons respond to appetitive events, such as …
Cholinergic interneurons control local circuit activity and cocaine conditioning
Cholinergic neurons are widespread, and pharmacological modulation of acetylcholine
receptors affects numerous brain processes, but such modulation entails side effects due to …
receptors affects numerous brain processes, but such modulation entails side effects due to …
Neurobiology of addiction
RA Wise - Current opinion in neurobiology, 1996 - Elsevier
Addictive drugs have habit-forming actions that can be localized to a variety of brain regions.
Recent advances in our understanding of the chemical 'trigger zones' in which individual …
Recent advances in our understanding of the chemical 'trigger zones' in which individual …
Nucleus accumbens neurons are innately tuned for rewarding and aversive taste stimuli, encode their predictors, and are linked to motor output
The nucleus accumbens (NAc) is a key component of the brain's reward pathway, yet little is
known of how NAc cells respond to primary rewarding or aversive stimuli. Here, naive rats …
known of how NAc cells respond to primary rewarding or aversive stimuli. Here, naive rats …