Cyclopropane-functionalized hydrocarbons are excellent fuels due their high energy
density. However, the organic synthesis of these molecules is challenging. In this work, we …

Streptomycetes are producers of a wide range of specialized metabolites of great medicinal
and industrial importance, such as antibiotics, antifungals, or pesticides. Having been the …

Quercetin is the most abundant polyphenolic flavonoid (flavonol subclass) in vegetal foods
and medicinal plants. This dietary chemopreventive agent has drawn significant interest for …

Plecomacrolides, such as concanamycins and bafilomycins, are potent and specific
inhibitors of vacuolar-type ATPase. Concanamycins are 18-membered macrolides with …

Background Butenyl-spinosyn, produced by Saccharopolyspora pogona, is a promising
biopesticide due to excellent insecticidal activity and broad pesticidal spectrum …

Microbial secondary metabolites are intensively explored due to their demands in
pharmaceutical, agricultural and food industries. Streptomyces are one of the largest …

Background AdpA is a global regulator of morphological differentiation and secondary
metabolism in Streptomyces, but the regulatory roles of the Streptomyces AdpA family on the …

Abstract The xenobiotic 2, 4, 6-trinitrotoluene (TNT) is a highly persistent environmental
contaminant, whose biotransformation by microorganisms has attracted renewed attention …

Pirin family proteins perform a variety of biological functions and widely exist in all living
organisms. A few studies have shown that Pirin family proteins may be involved in the …

The bacteria of the genus Streptomyces are the most valuable source of natural products of
industrial and medical importance. A recent explosion of Streptomyces genome sequence …