Photopharmacology is an attractive approach for achieving targeted drug action with the use
of light. In photopharmacology, molecular photoswitches are introduced into the structure of …

Molecular photoswitches enable dynamic control of processes with high spatiotemporal
precision, using light as external stimulus, and hence are ideal tools for different research …

Light-based therapeutic and imaging modalities, which emerge in clinical applications, rely
on molecular tools, such as photocleavable protecting groups and photoswitches that …

The clinical team attending to a patient upon a diagnosis is faced with two main questions:
what treatment, and at what dose? Clinical trials' results provide the basis for guidance and …

The circadian clock controls daily rhythms of physiological processes. The presence of the
clock mechanism throughout the body is hampering its local regulation by small molecules …

Photopharmacology relies on ligands that change their pharmacodynamics upon
photoisomerization. Many of these ligands are azobenzenes that are thermodynamically …

Glutamate transporters are cation-coupled secondary active membrane transporters that
clear the neurotransmitter L-glutamate from the synaptic cleft. These transporters are …

Photopharmacology addresses the challenge of drug selectivity and side effects through
creation of photoresponsive molecules activated with light with high spatiotemporal …

Azobenzene-based unnatural amino acid scaffolds via a Pd( ii )-catalyzed C(sp 3 )–H arylation
strategy - Chemical Communications (RSC Publishing) DOI:10.1039/D2CC04870A Royal …

Short, complementary DNA single strands with mismatched base pairs cannot undergo
spontaneous formation of duplex DNA (dsDNA). Mismatch binding ligands (MBLs) can …