Lagos bat virus, an under-reported rabies-related lyssavirus

J Coertse, M Geldenhuys, K le Roux, W Markotter - Viruses, 2021 - mdpi.com
Lagos bat virus (LBV), one of the 17 accepted viral species of the Lyssavirus genus, was the
first rabies-related virus described in 1956. This virus is endemic to the African continent and …

Interferon regulatory factors IRF1 and IRF7 directly regulate gene expression in bats in response to viral infection

AT Irving, Q Zhang, PS Kong, K Luko, P Rozario… - Cell reports, 2020 - cell.com
Bat cells and tissue have elevated basal expression levels of antiviral genes commonly
associated with interferon alpha (IFNα) signaling. Here, we show Interferon Regulatory …

Emerging horizon for bat borne viral zoonoses

V Beena, G Saikumar - VirusDisease, 2019 - Springer
Bats are the only flying placental mammals that constitute the second largest order of
mammals and present all around the world except in Arctic, Antarctica and a few oceanic …

[HTML][HTML] Zoonotic emergence at the animal-environment-human interface: the forgotten urban socio-ecosystems

G Dobigny, S Morand - Peer Community Journal, 2022 - peercommunityjournal.org
Zoonotic emergence requires spillover from animals to humans, hence animal-human
interactions. A lot has been emphasized on human intrusion into wild habitats (eg …

Seasonal shedding of coronavirus by straw-colored fruit bats at urban roosts in Africa

D Montecino-Latorre, T Goldstein, TR Kelly… - PLoS …, 2022 - journals.plos.org
The straw-colored fruit bat (Eidolon helvum) is a pteropodid whose conservation is crucial
for maintaining functional connectivity of plant populations in tropical Africa. Land …

Support for viral persistence in bats from age-specific serology and models of maternal immunity

AJ Peel, KS Baker, DTS Hayman, CC Broder… - Scientific reports, 2018 - nature.com
Spatiotemporally-localised prediction of virus emergence from wildlife requires focused
studies on the ecology and immunology of reservoir hosts in their native habitat. Reliable …

Lyssavirus vaccine with a chimeric glycoprotein protects across phylogroups

CR Fisher, DE Lowe, TG Smith, Y Yang, CL Hutson… - Cell reports, 2020 - cell.com
Rabies is nearly 100% lethal in the absence of treatment, killing an estimated 59,000 people
annually. Vaccines and biologics are highly efficacious when administered properly. Sixteen …

Maternal antibody and the maintenance of a lyssavirus in populations of seasonally breeding African bats

DTS Hayman, AD Luis, O Restif, KS Baker, AR Fooks… - PloS one, 2018 - journals.plos.org
Pathogens causing acute disease and death or lasting immunity require specific spatial or
temporal processes to persist in populations. Host traits, such as maternally-derived …

Experimental Lagos bat virus infection in straw-colored fruit bats: A suitable model for bat rabies in a natural reservoir species

L Begeman, R Suu-Ire, AC Banyard… - PLoS neglected …, 2020 - journals.plos.org
Rabies is a fatal neurologic disease caused by lyssavirus infection. Bats are important
natural reservoir hosts of various lyssaviruses that can be transmitted to people. The …

Surveillance for potentially zoonotic viruses in rodent and bat populations and behavioral risk in an agricultural settlement in Ghana

R Suu-Ire, E Obodai, SO Bel-Nono, WK Ampofo… - One Health …, 2022 - Springer
Abstract Background In Ghana, the conversion of land to agriculture, especially across the
vegetative belt has resulted in fragmented forest landscapes with increased interactions …