Promoter DNA methylation, which occurs on cytosine nucleotides across CpG islands,
results in gene silencing and represents a major epigenetic alteration in human cancer …

Background: Staging laparoscopy for gastric cancer is recommended to assess the tumor's
locoregional extension and exclude peritoneal disease. As there is no consensus on …

Objective: This prospective randomized multicenter study aims to evaluate the efficacy of
extensive intraoperative peritoneal lavage followed by intraperitoneal chemotherapy (EIPL …

Background Although positive peritoneal cytology is associated with poor prognosis, it has
not been found to be independently predictive of outcome when evaluated in context of post …

Detection of free gastric cancer cells in peritoneal lavages and ascites plays a vital role in
gastric cancer. However, due to the low content of cancer cells in patients' peritoneal …

Background Most previous studies concerning the impact of positive margins on patient
outcomes were based on patients with D1 lymphadenectomy. The prognostic significance of …

Peritoneal dissemination is established through a multistep process [1]. The first step is the
detachment of cancer cells from the serosal surface of the primary tumor; the detached …

Peritoneal metastasis (PM) is the mostcommon form of distant metastasis and one of the
leading causes of death in gastriccancer (GC). For locally advanced GC, clinical guidelines …

Background Complete resection with negative surgical margins has been a long‐held
surgical philosophy based on the concept that even minimal remaining cancer cells will …

Background Despite adjuvant chemotherapy, patients with advanced gastric cancer (AGC)
often develop recurrence, and the peritoneum is the most common site of recurrence …