Osteoporosis is a common disease with a strong genetic component characterized by
reduced bone mass, defects in the microarchitecture of bone tissue, and an increased risk of …

Osteoporosis is among the most common and costly diseases and is increasing in
prevalence owing to the ageing of our global population. Clinically defined largely through …

Osteoporosis is characterized by low bone mineral density and structural deterioration of
bone tissue, leading to an increased risk of fractures. It is the most common metabolic bone …

Osteoporosis is a complex human disease that results in increased susceptibility to fragility
fractures. It can be phenotypically characterized using several traits, including bone mineral …

Background Current genome-wide association studies (GWAS) are normally implemented in
a univariate framework and analyze different phenotypes in isolation. This univariate …

Introduction: Osteoporosis is characterized by low BMD. Studies have shown that B cells
may participate in osteoclastogenesis through expression of osteoclast‐related factors, such …

Common diseases result from the complex relationship between genetic and environmental
factors. The aim of this review is to provide perspective for a conceptual framework aimed at …

Congenital osteopenia is a bone demineralization condition that is associated with elevated
fracture risk in human infants. Here we show that Runx3, like Runx2, is expressed in …

Osteoporosis is characterized mainly by low bone mineral density (BMD). Many cytokines
and chemokines have been related with bone metabolism. Monocytes in the immune system …

Osteoporosis, the most prevalent metabolic bone disease among older people, increases
risk for low trauma hip fractures (HF) that are associated with high morbidity and mortality …