Comprehensive evaluation of deep and graph learning on drug–drug interactions prediction

X Lin, L Dai, Y Zhou, ZG Yu, W Zhang… - Briefings in …, 2023 - academic.oup.com
Recent advances and achievements of artificial intelligence (AI) as well as deep and graph
learning models have established their usefulness in biomedical applications, especially in …

Knowledge graphs meet multi-modal learning: A comprehensive survey

Z Chen, Y Zhang, Y Fang, Y Geng, L Guo… - ar** personalized diagnostic strategies and targeted treatments requires a deep
understanding of disease biology and the ability to dissect the relationship between …

Graph neural networks: foundation, frontiers and applications

L Wu, P Cui, J Pei, L Zhao, X Guo - … of the 28th ACM SIGKDD conference …, 2022 - dl.acm.org
The field of graph neural networks (GNNs) has seen rapid and incredible strides over the
recent years. Graph neural networks, also known as deep learning on graphs, graph …

MUFFIN: multi-scale feature fusion for drug–drug interaction prediction

Y Chen, T Ma, X Yang, J Wang, B Song, X Zeng - Bioinformatics, 2021 - academic.oup.com
Motivation Adverse drug–drug interactions (DDIs) are crucial for drug research and mainly
cause morbidity and mortality. Thus, the identification of potential DDIs is essential for …

A review of biomedical datasets relating to drug discovery: a knowledge graph perspective

S Bonner, IP Barrett, C Ye, R Swiers… - Briefings in …, 2022 - academic.oup.com
Drug discovery and development is a complex and costly process. Machine learning
approaches are being investigated to help improve the effectiveness and speed of multiple …

SumGNN: multi-typed drug interaction prediction via efficient knowledge graph summarization

Y Yu, K Huang, C Zhang, LM Glass, J Sun… - …, 2021 - academic.oup.com
Motivation Thanks to the increasing availability of drug–drug interactions (DDI) datasets and
large biomedical knowledge graphs (KGs), accurate detection of adverse DDI using …

Knowledge graphs and their applications in drug discovery

F MacLean - Expert opinion on drug discovery, 2021 - Taylor & Francis
Introduction Knowledge graphs have proven to be promising systems of information storage
and retrieval. Due to the recent explosion of heterogeneous multimodal data sources …

A biomedical knowledge graph-based method for drug–drug interactions prediction through combining local and global features with deep neural networks

ZH Ren, ZH You, CQ Yu, LP Li, YJ Guan… - Briefings in …, 2022 - academic.oup.com
Drug–drug interactions (DDIs) prediction is a challenging task in drug development and
clinical application. Due to the extremely large complete set of all possible DDIs, computer …

Editing factual knowledge and explanatory ability of medical large language models

D Xu, Z Zhang, Z Zhu, Z Lin, Q Liu, X Wu, T Xu… - Proceedings of the 33rd …, 2024 - dl.acm.org
Model editing aims to precisely alter the behaviors of large language models (LLMs) in
relation to specific knowledge, while leaving unrelated knowledge intact. This approach has …