[HTML][HTML] Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system

M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …

The roles of microglia and astrocytes in phagocytosis and myelination: Insights from the cuprizone model of multiple sclerosis

MK Sen, DA Mahns, JR Coorssen, PJ Shortland - Glia, 2022 - Wiley Online Library
In human demyelinating diseases such as multiple sclerosis (MS), an imbalance between
demyelination and remyelination can trigger progressive degenerative processes. The …

[HTML][HTML] Mitochondrial dysfunction and multiple sclerosis

IP Barcelos, RM Troxell, JS Graves - Biology, 2019 - mdpi.com
In recent years, several studies have examined the potential associations between
mitochondrial dysfunction and neurodegenerative diseases such as multiple sclerosis (MS) …

Regulatory T cells in multiple sclerosis and myasthenia gravis

KM Danikowski, S Jayaraman… - Journal of …, 2017 - Springer
Multiple sclerosis (MS) is a chronic debilitating disease of the central nervous system
primarily mediated by T lymphocytes with specificity to neuronal antigens in genetically …

[HTML][HTML] The cuprizone model: dos and do nots

J Zhan, T Mann, S Joost, N Behrangi, M Frank, M Kipp - Cells, 2020 - mdpi.com
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system. Various pre-clinical models with different specific features of the disease …

[HTML][HTML] Bile acid signaling in neurodegenerative and neurological disorders

SM Grant, S DeMorrow - International Journal of Molecular Sciences, 2020 - mdpi.com
Bile acids are commonly known as digestive agents for lipids. The mechanisms of bile acids
in the gastrointestinal track during normal physiological conditions as well as hepatic and …

[HTML][HTML] An overall view of the most common experimental models for multiple sclerosis

S Dedoni, M Scherma, C Camoglio, C Siddi… - Neurobiology of …, 2023 - Elsevier
Multiple sclerosis (MS) is a complex chronic disease with an unknown etiology. It is
considered an inflammatory demyelinating and neurodegenerative disorder of the central …

Animal models of multiple sclerosis: Focus on experimental autoimmune encephalomyelitis

I Bjelobaba, V Begovic‐Kupresanin… - Journal of …, 2018 - Wiley Online Library
Multiple sclerosis (MS) is a chronic, progressive disorder of the central nervous system
(CNS) that affects more than two million people worldwide. Several animal models resemble …

The multiple sclerosis gut microbiota: A systematic review

A Mirza, JD Forbes, F Zhu, CN Bernstein… - Multiple Sclerosis and …, 2020 - Elsevier
Background To systematically review and synthesize the literature on the multiple sclerosis
(MS) gut microbiota composition as compared to persons without MS. Methods We …

AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis

C Ma, S Li, Y Hu, Y Ma, Y Wu, C Wu, X Liu… - Journal of Experimental …, 2021 - rupress.org
The role of the PYHIN family member absent in melanoma 2 (AIM2), another important
inflammasome sensor, in EAE remains unclear. In this study, we found that AIM2 negatively …