MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches
The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …
molecular biology assuming protein-coding genes as unique functional biological effectors …
MALAT1: a potential biomarker in cancer
ZX Li, QN Zhu, HB Zhang, Y Hu, G Wang… - Cancer management …, 2018 - Taylor & Francis
Purpose The research of long non-coding RNAs (lncRNAs) has become a new passion with
the discovery of abundant new lncRNAs and extensive investigation of their roles in various …
the discovery of abundant new lncRNAs and extensive investigation of their roles in various …
Long non-coding RNA HIF1A-As2 and MYC form a double-positive feedback loop to promote cell proliferation and metastasis in KRAS-driven non-small cell lung …
K Yang, W Zhang, L Zhong, Y ** nuclear speckles
X Wang, C Liu, S Zhang, H Yan, L Zhang, A Jiang… - Developmental cell, 2021 - cell.com
Summary N6-methyladenosine (m 6 A), one of the most prevalent RNA post-transcriptional
modifications, is involved in numerous biological processes. In previous studies, the …
modifications, is involved in numerous biological processes. In previous studies, the …
Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1‐EEF1A1 Axis
Epigenetic dysregulation is reported in multiple cancers including Ewing sarcoma (EwS).
However, the epigenetic networks underlying the maintenance of oncogenic signaling and …
However, the epigenetic networks underlying the maintenance of oncogenic signaling and …
Expanding the molecular diversity of CIC-rearranged sarcomas with novel and very rare partners
Capicua transcriptional repressor (CIC)-rearranged sarcoma represents a distinct pathologic
entity, which constitutes the second most prevalent category of undifferentiated round cell …
entity, which constitutes the second most prevalent category of undifferentiated round cell …
IL-8 secreted from M2 macrophages promoted prostate tumorigenesis via STAT3/MALAT1 pathway
T Zheng, G Ma, M Tang, Z Li, R Xu - International Journal of Molecular …, 2018 - mdpi.com
Prostate cancer (PCa) is a major health problem in males. Metastasis-associated with lung
adenocarcinoma transcript-1 (MALAT1), which is overexpressed in PCa tissue, is associated …
adenocarcinoma transcript-1 (MALAT1), which is overexpressed in PCa tissue, is associated …
The involvement of long non-coding RNAs in bone
C Aurilia, S Donati, G Palmini, F Miglietta… - International Journal of …, 2021 - mdpi.com
A harmonious balance between osteoblast and osteoclast activity guarantees optimal bone
formation and resorption, pathological conditions affecting the bone may arise. In recent …
formation and resorption, pathological conditions affecting the bone may arise. In recent …
CD74 promotes perineural invasion of cancer cells and mediates neuroplasticity via the AKT/EGR-1/GDNF axis in pancreatic ductal adenocarcinoma
JF Zhang, LY Tao, MW Yang, DP Xu, SH Jiang, XL Fu… - Cancer Letters, 2021 - Elsevier
Perineural invasion (PNI) is a common feature of pancreatic ductal adenocarcinoma (PDAC)
and is one of the important causes of local recurrence in resected pancreatic cancer, but the …
and is one of the important causes of local recurrence in resected pancreatic cancer, but the …
Super-enhancer-associated MEIS1 promotes transcriptional dysregulation in Ewing sarcoma in co-operation with EWS-FLI1
L Lin, M Huang, X Shi, A Mayakonda, K Hu… - Nucleic acids …, 2019 - academic.oup.com
As the second most common malignant bone tumor in children and adolescents, Ewing
sarcoma is initiated and exacerbated by a chimeric oncoprotein, most commonly, EWS-FLI1 …
sarcoma is initiated and exacerbated by a chimeric oncoprotein, most commonly, EWS-FLI1 …