The most common and aggressive primitive intracranial tumor of the central nervous system
is the glioma. The blood–brain barrier (BBB) has proven to be a significant obstacle to the …

Simple Summary Glioblastoma multiforme (GB) and neuroblastomas (NBs) are nervous
system cancers that are difficult to diagnosis and treat. Chlorotoxin (CTX), is a peptide …

Background: Glioblastoma (GBM) is categorized as a grade IV astrocytoma by the World
Health Organization (WHO), representing the most aggressive and prevalent form of glioma …

Resistance to temozolomide (TMZ) is the main cause of death in glioblastoma multiforme
(GBM). The use of nanocarriers for drug delivery applications is one of the known …

The focus of this review is on chitosan and the functionalization of chitosan nanoparticles
using chlorotoxin as a targeting agent in drug delivery and treatment of glioma. Chitosan has …

Background: A large number of studies have been conducted on the treatment of
glioblastoma multiforme (GBM). Chemotherapeutic drugs cannot penetrate deeply into the …

Cancers with a high capability for angiogenesis are frequently regarded as being difficult to
treat. Anti-angiogenesis drugs are considered the primary therapy for these types of cancers …

Introduction: Breast cancer is the most common form of cancer among women, it is critical to
identify potential targets and prognostic biomarkers. Ferroptosis combined with immunity …

Alternative pathways frequently operate as the origins of resistance to drugs that block the
vascular endothelial growth factor (VEGF) pathway. To find possible therapeutic targets and …

Glioblastoma multiforme (GBM) resistance to anti-angiogenesis drugs results in recurrence
of the disease which leads to death. The resistance to anti-angiogenesis drugs that target …