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Oocyte–somatic cell interactions in the human ovary—novel role of bone morphogenetic proteins and growth differentiation factors
BACKGROUND Initially identified for their capability to induce heterotopic bone formation,
bone morphogenetic proteins (BMPs) are multifunctional growth factors that belong to the …
bone morphogenetic proteins (BMPs) are multifunctional growth factors that belong to the …
GDF-9 and BMP-15 direct the follicle symphony
A Sanfins, P Rodrigues, DF Albertini - Journal of assisted reproduction and …, 2018 - Springer
Understanding the physiology underlying the complex dialog between the oocyte and its
surrounding somatic cells within the ovarian follicle has been crucial in defining optimal …
surrounding somatic cells within the ovarian follicle has been crucial in defining optimal …
Genetics of primary ovarian insufficiency
Primary ovarian insufficiency (POI) is characterized by a loss of ovarian function before the
age of 40 and account for one major cause of female infertility. POI relevance is continuously …
age of 40 and account for one major cause of female infertility. POI relevance is continuously …
The fundamental role of bone morphogenetic protein 15 in ovarian function and its involvement in female fertility disorders
BACKGROUND A large number of studies have contributed to understanding the general
mechanisms driving ovarian folliculogenesis in humans and show a complex endocrine …
mechanisms driving ovarian folliculogenesis in humans and show a complex endocrine …
[PDF][PDF] Tissue-specific mRNA expression profile of BMP15 gene in goat
M Mohammadabadi, M Soflaei - Agric Biotechnol J, 2020 - academia.edu
Materials and Methods Tissue samples (3 repetitions of each tissue) were taken from ovary,
uterus, uterine horn, oviduct, skeletal muscle, subcutaneous fat, heart, liver, lung, kidney …
uterus, uterine horn, oviduct, skeletal muscle, subcutaneous fat, heart, liver, lung, kidney …
Oocyte-secreted factors synergize with FSH to promote aromatase expression in primary human cumulus cells
E Hobeika, M Armouti, H Kala, MA Fierro… - The Journal of …, 2019 - academic.oup.com
Context The role of growth differentiation factor 9 (GDF9) and bone morphogenetic protein
15 (BMP15) on aromatase regulation is poorly understood in humans. Objective Determine …
15 (BMP15) on aromatase regulation is poorly understood in humans. Objective Determine …
Fundamental role of BMP15 in human ovarian folliculogenesis revealed by null and missense mutations associated with primary ovarian insufficiency
R Rossetti, I Ferrari, I Bestetti, S Moleri… - Human …, 2020 - Wiley Online Library
Abstract Bone morphogenetic protein 15 (BMP15) encodes an oocyte factor with a relevant
role for folliculogenesis as homodimer or cumulin heterodimer (BMP15‐GDF9) …
role for folliculogenesis as homodimer or cumulin heterodimer (BMP15‐GDF9) …
Connecting links between genetic factors defining ovarian reserve and recurrent miscarriages
DD Dean, S Agarwal, P Tripathi - Journal of assisted reproduction and …, 2018 - Springer
Abstract Purpose Approximately 1–2% of the women faces three or more successive
spontaneous miscarriages termed as recurrent miscarriage (RM). Many clinical factors have …
spontaneous miscarriages termed as recurrent miscarriage (RM). Many clinical factors have …
Evolutionary origin of bone morphogenetic protein 15 and growth and differentiation factor 9 and differential selective pressure between mono-and polyovulating …
Abstract Bone morphogenetic protein 15 (BMP15) and growth and differentiation factor 9
(GDF9) are TGFbeta-like oocyte-derived growth factors involved in ovarian folliculogenesis …
(GDF9) are TGFbeta-like oocyte-derived growth factors involved in ovarian folliculogenesis …
Maximum‐likelihood approaches reveal signatures of positive selection in BMP15 and GDF9 genes modulating ovarian function in mammalian female fertility
HI Ahmad, G Liu, X Jiang, SG Edallew… - Ecology and …, 2017 - Wiley Online Library
Bone morphogenetic proteins (BMP s) and the growth factors (GDF s) play an important role
in ovarian folliculogenesis and essential regulator of processes of numerous granulosa …
in ovarian folliculogenesis and essential regulator of processes of numerous granulosa …