The need to overcome ever-increasing cases of antifungal resistance and circumvent side
effects and drug interactions related to currently available drugs has impelled the demand to …

A pharmacophore system has been found as 1, 2, 3‐triazole, a five‐membered heterocycle
ring with nitrogen heteroatoms. These heterocyclic compounds can be produced using …

Abstract α-Glucosidase is an important therapeutic target of diabetes mellitus. To find potent
α-glucosidase inhibitors, thirty-one β-carboline derivatives containing piperazine moieties …

Bacterial resistance remains a significant threat and a leading cause of death worldwide,
despite massive attempts to control infections. In an effort to develop biologically active …

Plant bacterial diseases can potentially damage agricultural products around the world, and
few effective bactericides can manage these infections. Herein, to sequentially explore …

A series of 19 novel eugenol derivatives containing a 1, 2, 3-triazole moiety was synthesized
via a two-step process, with the key step being a copper (I)-catalyzed azide–alkyne …

The β-carboline skeleton is prevalent in a vast collection of naturally present alkaloids. Most
of these alkaloids and their derivatives have been found to show significant biological …

Triazole groups play an important role in the construction of agricultural bioactive molecules,
often acting as linking units to organically graft different pharmacophore groups, so as to …

The discovery of antifungal agents with novel structure, broad-spectrum, low toxicity, and
high efficiency has been the focus of medicinal chemists. Over the past decades, β-carboline …

Neuropsychiatric disorders are diseases of the central nervous system (CNS) which are
characterised by complex pathomechanisms that including homeostatic failure, malfunction …