Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Crystal structures of protein-bound cyclic peptides
Cyclization is an important post-translational modification of peptides and proteins that
confers key advantages such as protection from proteolytic degradation, altered solubility …
confers key advantages such as protection from proteolytic degradation, altered solubility …
[HTML][HTML] Neutron crystallography for the study of hydrogen bonds in macromolecules
The hydrogen bond (H bond) is one of the most important interactions that form the
foundation of secondary and tertiary protein structure. Beyond holding protein structures …
foundation of secondary and tertiary protein structure. Beyond holding protein structures …
Advances in protein and small-molecule charge-density refinement methods using MoPro
With an increasing number of biological macromolecule structures solved at ultra-high
resolution and with the advances of supramolecular chemistry, it becomes necessary to …
resolution and with the advances of supramolecular chemistry, it becomes necessary to …
The backrub motion: how protein backbone shrugs when a sidechain dances
Surprisingly, the frozen structures from ultra-high-resolution protein crystallography reveal a
prevalent, but subtle, mode of local backbone motion coupled to much larger, two-state …
prevalent, but subtle, mode of local backbone motion coupled to much larger, two-state …
Charge-density analysis of an iron–sulfur protein at an ultra-high resolution of 0.48 Å
Y Hirano, K Takeda, K Miki - Nature, 2016 - nature.com
The fine structures of proteins, such as the positions of hydrogen atoms, distributions of
valence electrons and orientations of bound waters, are critical factors for determining the …
valence electrons and orientations of bound waters, are critical factors for determining the …
On the application of an experimental multipolar pseudo-atom library for accurate refinement of small-molecule and protein crystal structures
B Zarychta, V Pichon-Pesme, B Guillot… - Foundations of …, 2007 - journals.iucr.org
With an increasing number of biomacromolecular crystal structures being measured to ultra-
high resolution, it has become possible to extend to large systems experimental charge …
high resolution, it has become possible to extend to large systems experimental charge …
Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Atomic resolution structures of trypsin acyl-enzymes and a tetrahedral intermediate analog,
along with previously solved structures representing the Michaelis complex, are used to …
along with previously solved structures representing the Michaelis complex, are used to …
Crystal structure of fatty acid amide hydrolase bound to the carbamate inhibitor URB597: discovery of a deacylating water molecule and insight into enzyme …
M Mileni, S Kamtekar, DC Wood, TE Benson… - Journal of molecular …, 2010 - Elsevier
The endocannabinoid system regulates a wide range of physiological processes including
pain, inflammation, and cognitive/emotional states. URB597 is one of the best characterized …
pain, inflammation, and cognitive/emotional states. URB597 is one of the best characterized …
Solvation free energy as a measure of hydrophobicity: application to serine protease binding interfaces
Solvation and hydrophobicity play a key role in a variety of biological mechanisms. In
substrate binding, but also in structure-based drug design, the thermodynamic properties of …
substrate binding, but also in structure-based drug design, the thermodynamic properties of …
Triclinic lysozyme at 0.65 Å resolution
The crystal structure of triclinic hen egg-white lysozyme (HEWL) has been refined against
diffraction data extending to 0.65 Å resolution measured at 100 K using synchrotron …
diffraction data extending to 0.65 Å resolution measured at 100 K using synchrotron …