Online adaptive radiation therapy

S Lim-Reinders, BM Keller, S Al-Ward, A Sahgal… - International Journal of …, 2017 - Elsevier
The current paradigm of radiation therapy has the treatment planned on a snapshot dataset
of the patient's anatomy taken at the time of simulation. Throughout the course of treatment …

Nuts and bolts of 4D-MRI for radiotherapy

B Stemkens, ES Paulson… - Physics in Medicine & …, 2018 - iopscience.iop.org
Magnetic resonance imaging (MRI) is increasingly being used in the radiotherapy workflow
because of its superior soft tissue contrast and high flexibility in contrast. In addition to …

Towards fast online intrafraction replanning for free-breathing stereotactic body radiation therapy with the MR-linac

C Kontaxis, GH Bol, B Stemkens… - Physics in Medicine …, 2017 - iopscience.iop.org
The hybrid MRI-radiotherapy machines, like the MR-linac (Elekta AB, Stockholm, Sweden)
installed at the UMC Utrecht (Utrecht, The Netherlands), will be able to provide real-time …

Image-driven, model-based 3D abdominal motion estimation for MR-guided radiotherapy

B Stemkens, RHN Tijssen… - Physics in Medicine …, 2016 - iopscience.iop.org
Respiratory motion introduces substantial uncertainties in abdominal radiotherapy for which
traditionally large margins are used. The MR-Linac will open up the opportunity to acquire …

MRI-guidance for motion management in external beam radiotherapy: current status and future challenges

C Paganelli, B Whelan, M Peroni… - Physics in Medicine …, 2018 - iopscience.iop.org
High precision conformal radiotherapy requires sophisticated imaging techniques to aid in
target localisation for planning and treatment, particularly when organ motion due to …

An improved optical flow tracking technique for real-time MR-guided beam therapies in moving organs

C Zachiu, N Papadakis, M Ries… - Physics in Medicine …, 2015 - iopscience.iop.org
Magnetic resonance (MR) guided high intensity focused ultrasound and external beam
radiotherapy interventions, which we shall refer to as beam therapies/interventions, are …

[HTML][HTML] Magnetic resonance imaging in precision radiation therapy for lung cancer

H Bainbridge, A Salem, RHN Tijssen… - … lung cancer research, 2017 - ncbi.nlm.nih.gov
Radiotherapy remains the cornerstone of curative treatment for inoperable locally advanced
lung cancer, given concomitantly with platinum-based chemotherapy. With poor overall …

Real‐time 3D motion estimation from undersampled MRI using multi‐resolution neural networks

ML Terpstra, M Maspero, T Bruijnen… - Medical …, 2021 - Wiley Online Library
Purpose: To enable real‐time adaptive magnetic resonance imaging–guided radiotherapy
(MRIgRT) by obtaining time‐resolved three‐dimensional (3D) deformation vector fields …

A modern review of the uncertainties in volumetric imaging of respiratory‐induced target motion in lung radiotherapy

I Vergalasova, J Cai - Medical physics, 2020 - Wiley Online Library
Radiotherapy has become a critical component for the treatment of all stages and types of
lung cancer, often times being the primary gateway to a cure. However, given that radiation …

Accelerated respiratory‐resolved 4D‐MRI with separable spatio‐temporal neural networks

ML Terpstra, M Maspero, JJC Verhoeff… - Medical …, 2023 - Wiley Online Library
Background Respiratory‐resolved four‐dimensional magnetic resonance imaging (4D‐MRI)
provides essential motion information for accurate radiation treatments of mobile tumors …