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Advanced physical techniques for gene delivery based on membrane perforation
X Du, J Wang, Q Zhou, L Zhang, S Wang, Z Zhang… - Drug …, 2018 - Taylor & Francis
Gene delivery as a promising and valid tool has been used for treating many serious
diseases that conventional drug therapies cannot cure. Due to the advancement of physical …
diseases that conventional drug therapies cannot cure. Due to the advancement of physical …
High-throughput sequencing of single neuron projections reveals spatial organization in the olfactory cortex
In most sensory modalities, neuronal connectivity reflects behaviorally relevant stimulus
features, such as spatial location, orientation, and sound frequency. By contrast, the …
features, such as spatial location, orientation, and sound frequency. By contrast, the …
Delivery systems for mitochondrial gene therapy: a review
Mitochondria are membrane-bound cellular organelles of high relevance responsible for the
chemical energy production used in most of the biochemical reactions of cells. Mitochondria …
chemical energy production used in most of the biochemical reactions of cells. Mitochondria …
Self‐powered intracellular drug delivery by a biomechanical energy‐driven triboelectric nanogenerator
Nondestructive, high‐efficiency, and on‐demand intracellular drug/biomacromolecule
delivery for therapeutic purposes remains a great challenge. Herein, a biomechanical …
delivery for therapeutic purposes remains a great challenge. Herein, a biomechanical …
Long-range functional loops in the mouse olfactory system and their roles in computing odor identity
Elucidating the neural circuits supporting odor identification remains an open challenge.
Here, we analyze the contribution of the two output cell types of the mouse olfactory bulb …
Here, we analyze the contribution of the two output cell types of the mouse olfactory bulb …
Molecular characterization of projection neuron subtypes in the mouse olfactory bulb
Projection neurons (PNs) in the mammalian olfactory bulb (OB) receive input from the nose
and project to diverse cortical and subcortical areas. Morphological and physiological …
and project to diverse cortical and subcortical areas. Morphological and physiological …
Neurogenesis dynamics in the olfactory bulb: deciphering circuitry organization, function, and adaptive plasticity
Adult neurogenesis persists after birth in the subventricular zone, with new neurons
migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they …
migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they …
Functional and multiscale 3D structural investigation of brain tissue through correlative in vivo physiology, synchrotron microtomography and volume electron …
Understanding the function of biological tissues requires a coordinated study of physiology
and structure, exploring volumes that contain complete functional units at a detail that …
and structure, exploring volumes that contain complete functional units at a detail that …
Flexible electronics and materials for synchronized stimulation and monitoring in multi‐encephalic regions
Simultaneous neuron stimulation and biophysiological sensing in multi‐encephalic regions
can lead to profound understanding of neural pathways, neurotransmitter transportation, and …
can lead to profound understanding of neural pathways, neurotransmitter transportation, and …
[HTML][HTML] Femtosecond laser preparation of resin embedded samples for correlative microscopy workflows in life sciences
Correlative multimodal imaging is a useful approach to investigate complex structural
relations in life sciences across multiple scales. For these experiments, sample preparation …
relations in life sciences across multiple scales. For these experiments, sample preparation …