How the immune system shapes atherosclerosis: roles of innate and adaptive immunity
Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in
preclinical models and emerging evidence in humans have established the crucial roles of …
preclinical models and emerging evidence in humans have established the crucial roles of …
Dendritic cell migration in inflammation and immunity
J Liu, X Zhang, Y Cheng, X Cao - Cellular & molecular immunology, 2021 - nature.com
Dendritic cells (DCs) are the key link between innate immunity and adaptive immunity and
play crucial roles in both the promotion of immune defense and the maintenance of immune …
play crucial roles in both the promotion of immune defense and the maintenance of immune …
YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8+ T cells
Despite tumor-associated macrophages (TAMs) playing a key role in sha** the tumor
microenvironment (TME), the mechanisms by which TAMs influence the TME and contribute …
microenvironment (TME), the mechanisms by which TAMs influence the TME and contribute …
[HTML][HTML] Type I interferon activates MHC class I-dressed CD11b+ conventional dendritic cells to promote protective anti-tumor CD8+ T cell immunity
Tumor-infiltrating dendritic cells (DCs) assume varied functional states that impact anti-tumor
immunity. To delineate the DC states associated with productive anti-tumor T cell immunity …
immunity. To delineate the DC states associated with productive anti-tumor T cell immunity …
Designing cancer immunotherapies that engage T cells and NK cells
O Kyrysyuk, KW Wucherpfennig - Annual review of immunology, 2023 - annualreviews.org
T cells and natural killer (NK) cells have complementary roles in tumor immunity, and dual T
cell and NK cell attack thus offers opportunities to deepen the impact of immunotherapy …
cell and NK cell attack thus offers opportunities to deepen the impact of immunotherapy …
Dendritic cell regulation of T helper cells
As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …
The dynamics of the skin's immune system
AV Nguyen, AM Soulika - International journal of molecular sciences, 2019 - mdpi.com
The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …
chemical, and microbiological barriers, to protect the host from external insults. In addition …
Dendritic cells and their role in immunotherapy
Despite significant advances in the field of cancer immunotherapy, the majority of patients
still do not benefit from treatment and must rely on traditional therapies. Dendritic cells have …
still do not benefit from treatment and must rely on traditional therapies. Dendritic cells have …
Dendritic cells in cancer immunology
TL Murphy, KM Murphy - Cellular & molecular immunology, 2022 - nature.com
The clinical success of immune checkpoint therapy (ICT) has produced explosive growth in
tumor immunology research because ICT was discovered through basic studies of immune …
tumor immunology research because ICT was discovered through basic studies of immune …
PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer
Inhibiting the programmed death-1 (PD-1) pathway is one of the most effective approaches
to cancer immunotherapy, but its mechanistic basis remains incompletely understood …
to cancer immunotherapy, but its mechanistic basis remains incompletely understood …