Interpretation of the effect of CYP2C9, VKORC1 and CYP4F2 variants on warfarin dosing adjustment in Turkey
It was aimed to underline the importance and explain the meaning of genetic testing in
warfarin dosing and investigate and evaluate the contributions of the CYP2C9, VKORC1 …
warfarin dosing and investigate and evaluate the contributions of the CYP2C9, VKORC1 …
Determining the adjusted initial treatment dose of warfarin anticoagulant medicine using kernel-based support vector regression
Background and objective A novel research field in bioinformatics is pharmacogenomics
and the corresponding applications of artificial intelligence tools. Pharmacogenomics is the …
and the corresponding applications of artificial intelligence tools. Pharmacogenomics is the …
Pharmacogenomics of anticoagulation therapy: the last 10 years
G Ragia, VG Manolopoulos - Pharmacogenomics, 2019 - Taylor & Francis
Since 2009, six main developments have occurred in this field: several RCTs aiming to
assess the safety and clinical utility of newly developed pharmacogenomic-guided dosing …
assess the safety and clinical utility of newly developed pharmacogenomic-guided dosing …
Evaluation of a warfarin dosing algorithm including CYP2C9, VKORC1, and CYP4F2 polymorphisms and non-genetic determinants for the Iranian population
M Farajzadeh-Dehkordi, F Samiee-Rad… - Pharmacological …, 2023 - Springer
Background The response to warfarin, as an oral anticoagulant agent, varies widely among
patients from different ethnic groups. In this study, we tried to ascertain and determine the …
patients from different ethnic groups. In this study, we tried to ascertain and determine the …
Pharmacogenomics-based practice in North Cyprus: its adoption by pharmacists and their attitudes and knowledge
Background Pharmacogenomics is a branch of biotechnological science integrating
medicine, pharmacology, and genomics techniques. Moreover, it focuses on creating drug …
medicine, pharmacology, and genomics techniques. Moreover, it focuses on creating drug …
Warfarin pharmacogenomics in African populations: the importance of ethnicity-based algorithms
Full article: Warfarin Pharmacogenomics in African Populations: The Importance of Ethnicity-Based
Algorithms Skip to Main Content Taylor and Francis Online homepage Taylor and Francis …
Algorithms Skip to Main Content Taylor and Francis Online homepage Taylor and Francis …
A novel acenocoumarol pharmacogenomic dosing algorithm for the Greek population of EU-PACT trial
G Ragia, V Kolovou, G Kolovou… - …, 2017 - Taylor & Francis
Aim: To generate and validate a pharmacogenomic-guided (PG) dosing algorithm for
acenocoumarol in the Greek population. To compare its performance with other PG …
acenocoumarol in the Greek population. To compare its performance with other PG …
Allergy-specific phenome-wide association study for immunogenes in Turkish children
To dissect the role of immunogenetics in allergy and asthma, we performed a phenome-
wide association study in 974 Turkish children selected from a cross-sectional study …
wide association study in 974 Turkish children selected from a cross-sectional study …
Nutritional habits, lifestyle, and genetic predisposition in cardiovascular and metabolic traits in Turkish population
Objectives Cardiovascular and metabolic traits (CMT) are influenced by complex interactive
processes including diet, lifestyle, and genetic predisposition. The present study …
processes including diet, lifestyle, and genetic predisposition. The present study …
Haplotype analysis of non-HLA immunogenetic loci in Turkish and worldwide populations
S Karaca, M Karaca, E Civelek, RK Ozgul, BE Sekerel… - Gene, 2016 - Elsevier
Immunogenes (ie, genes related to the immune system and its functions) are involved in the
predisposition to numerous traits and their variation contributes to the phenotypic variability …
predisposition to numerous traits and their variation contributes to the phenotypic variability …