Malaria in Brazil, Colombia, Peru and Venezuela: current challenges in malaria control and elimination

J Recht, AM Siqueira, WM Monteiro, SM Herrera… - Malaria journal, 2017 - Springer
In spite of significant progress towards malaria control and elimination achieved in South
America in the 2000s, this mosquito-transmitted tropical disease remains an important public …

Clinical impact of vivax malaria: a collection review

AP Phyo, P Dahal, M Mayxay, EA Ashley - PLoS Medicine, 2022 - journals.plos.org
Background Plasmodium vivax infects an estimated 7 million people every year. Previously,
vivax malaria was perceived as a benign condition, particularly when compared to …

Management of relapsing Plasmodium vivax malaria

CS Chu, NJ White - Expert review of anti-infective therapy, 2016 - Taylor & Francis
Introduction: Relapses are important contributors to illness and morbidity in Plasmodium
vivax and P. ovale infections. Relapse prevention (radical cure) with primaquine is required …

The immunological balance between host and parasite in malaria

K Deroost, TT Pham, G Opdenakker… - FEMS microbiology …, 2016 - academic.oup.com
Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Evaluation of splenic accumulation and colocalization of immature reticulocytes and Plasmodium vivax in asymptomatic malaria: A prospective human splenectomy …

S Kho, L Qotrunnada, L Leonardo, B Andries… - PLoS …, 2021 - journals.plos.org
Background A very large biomass of intact asexual-stage malaria parasites accumulates in
the spleen of asymptomatic human individuals infected with Plasmodium vivax. The …

Phase 1/2a Trial of Plasmodium vivax Malaria Vaccine Candidate VMP001/AS01B in Malaria-Naive Adults: Safety, Immunogenicity, and Efficacy

JW Bennett, A Yadava, D Tosh… - PLoS neglected …, 2016 - journals.plos.org
Background A vaccine to prevent infection and disease caused by Plasmodium vivax is
needed both to reduce the morbidity caused by this parasite and as a key component in …

Biological activity of 1, 2, 3-triazole-2-amino-1, 4-naphthoquinone derivatives and their evaluation as therapeutic strategy for malaria control

RMC Souza, LMLM Pimentel, LKM Ferreira… - European journal of …, 2023 - Elsevier
Malaria can be caused by several Plasmodium species and the development of an effective
vaccine is challenging. Currently, the most effective tool to control the disease is the …

Epidemiology of Plasmodium vivax malaria in Peru

A Rosas-Aguirre, D Gamboa… - … american Journal of …, 2016 - pmc.ncbi.nlm.nih.gov
Malaria in Peru, dominated by Plasmodium vivax, remains a public health problem. The
1990s saw newly epidemic malaria emerge, primarily in the Loreto Department in the …

African Plasmodium vivax malaria improbably rare or benign

JK Baird - Trends in Parasitology, 2022 - cell.com
The overwhelming dominance of Duffy blood group negativity among most people living in
sub-Saharan Africa has been considered the basis of their protection from endemic …

Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics

C Bourgard, L Albrecht, ACAV Kayano… - Frontiers in cellular …, 2018 - frontiersin.org
During the last decade, the vast omics field has revolutionized biological research,
especially the genomics, transcriptomics and proteomics branches, as technological tools …