mTOR as a central hub of nutrient signalling and cell growth

J Kim, KL Guan - Nature cell biology, 2019 - nature.com
The highly conserved protein kinase mechanistic target of rapamycin (mTOR; originally
known as mammalian target of rapamycin) is a central cell growth regulator connecting …

Role of sugar and auxin crosstalk in plant growth and development

BS Mishra, M Sharma, A Laxmi - Physiologia Plantarum, 2022 - Wiley Online Library
Under the natural environment, nutrient signals interact with phytohormones to coordinate
and reprogram plant growth and survival. Sugars are important molecules that control …

Differential TOR activation and cell proliferation in Arabidopsis root and shoot apexes

X Li, W Cai, Y Liu, H Li, L Fu, Z Liu… - Proceedings of the …, 2017 - National Acad Sciences
The developmental plasticity of plants relies on the remarkable ability of the meristems to
integrate nutrient and energy availability with environmental signals. Meristems in root and …

Dynamic and diverse sugar signaling

L Li, J Sheen - Current opinion in plant biology, 2016 - Elsevier
Highlights•Emerging sugar signals are discussed.•Direct sugar sensing and signaling is
triggered via sugar-binding sensors.•Sugar-derived metabolites modulate energy sensors …

SnRK1 activates autophagy via the TOR signaling pathway in Arabidopsis thaliana

J Soto-Burgos, DC Bassham - PloS one, 2017 - journals.plos.org
Autophagy is a degradation process in which cells break down and recycle their cytoplasmic
contents when subjected to environmental stress or during cellular remodeling. The …

TOR signaling in plants: conservation and innovation

L Shi, Y Wu, J Sheen - Development, 2018 - journals.biologists.com
Target of rapamycin (TOR) is an evolutionarily conserved protein kinase that plays a central
role in both plants and animals, despite their distinct developmental programs and survival …

SnRK1 and TOR: modulating growth–defense trade-offs in plant stress responses

L Margalha, A Confraria… - Journal of experimental …, 2019 - academic.oup.com
The evolutionarily conserved protein kinase complexes SnRK1 and TOR are central
metabolic regulators essential for plant growth, development, and stress responses. They …

Integration of nutrient, energy, light, and hormone signalling via TOR in plants

Y Wu, L Shi, L Li, L Fu, Y Liu, Y **ong… - Journal of experimental …, 2019 - academic.oup.com
The multidomain target of rapamycin (TOR) is an atypical serine/threonine protein kinase
resembling phosphatidylinositol lipid kinases, but retains high sequence identity and serves …

TOR and SnRK1 signaling pathways in plant response to abiotic stresses: do they always act according to the “yin-yang” model?

M Rodriguez, R Parola, S Andreola, C Pereyra… - Plant Science, 2019 - Elsevier
Plants are sessile photo-autotrophic organisms continuously exposed to a variety of
environmental stresses. Monitoring the sugar level and energy status is essential, since this …

The plant energy sensor: evolutionary conservation and divergence of SnRK1 structure, regulation, and function

T Broeckx, S Hulsmans, F Rolland - Journal of experimental …, 2016 - academic.oup.com
Abstract The SnRK1 (SNF1-related kinase 1) kinases are the plant cellular fuel gauges,
activated in response to energy-depleting stress conditions to maintain energy homeostasis …