Despite its apparent simplicity, the nematode worm Caenorhabditis elegans has developed
into an important model for biomedical research, particularly in the functional …

The genome sequence of an organism is an information resource unlike any that biologists
have previously had access to. But the value of the genome is only as good as its …

Abstract WormBase (https://wormbase. org/) is a mature Model Organism Information
Resource supporting researchers using the nematode Caenorhabditis elegans as a model …

As vertebrate genome sequences near completion and research refocuses to their analysis,
the issue of effective genome annotation display becomes critical. A mature web tool for …

Abstract MicroRNAs (miRNAs) are∼ 22-nucleotide endogenous RNAs that often repress the
expression of complementary messenger RNAs. In animals, miRNAs derive from …

To initiate studies on how protein-protein interaction (or “interactome”) networks relate to
multicellular functions, we have mapped a large fraction of the Caenorhabditis elegans …

Abstract The Sequence Ontology (SO) is a structured controlled vocabulary for the parts of a
genomic annotation. SO provides a common set of terms and definitions that will facilitate …

The Generic Model Organism System Database Project (GMOD) seeks to develop reusable
software components for model organism system databases. In this paper we describe the …

The soil nematodes Caenorhabditis briggsae and Caenorhabditis elegans diverged from a
common ancestor roughly 100 million years ago and yet are almost indistinguishable by …

Background Microbial inhabitants of soils are important to ecosystem and planetary
functions, yet there are large gaps in our knowledge of their diversity and ecology. The …