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[HTML][HTML] Mechanisms regulating neuromuscular junction development and function and causes of muscle wasting
LA Tintignac, HR Brenner… - Physiological …, 2015 - journals.physiology.org
The neuromuscular junction is the chemical synapse between motor neurons and skeletal
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …
Development of the vertebrate neuromuscular junction
▪ Abstract We describe the formation, maturation, elimination, maintenance, and
regeneration of vertebrate neuromuscular junctions (NMJs), the best studied of all synapses …
regeneration of vertebrate neuromuscular junctions (NMJs), the best studied of all synapses …
Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies
W Hoch, J McConville, S Helms, J Newsom-Davis… - Nature medicine, 2001 - nature.com
Myasthenia gravis (MG) is an antibody-mediated autoimmune disease of the neuromuscular
junction. In approximately 80% of patients, auto-antibodies to the muscle nicotinic …
junction. In approximately 80% of patients, auto-antibodies to the muscle nicotinic …
Induction, assembly, maturation and maintenance of a postsynaptic apparatus
The postsynaptic apparatus of the skeletal neuromuscular junction, like that of other
synapses, contains a high-density patch of neurotransmitter receptors that is closely …
synapses, contains a high-density patch of neurotransmitter receptors that is closely …
Anti-LRP4 autoantibodies in AChR-and MuSK-antibody-negative myasthenia gravis
A Pevzner, B Schoser, K Peters, NC Cosma… - Journal of …, 2012 - Springer
Myasthenia gravis (MG) is an autoimmune disorder characterized by a defect in synaptic
transmission at the neuromuscular junction causing fluctuating muscle weakness with a …
transmission at the neuromuscular junction causing fluctuating muscle weakness with a …
Autoantibodies to lipoprotein-related protein 4 in patients with double-seronegative myasthenia gravis
B Zhang, JS Tzartos, M Belimezi, S Ragheb… - Archives of …, 2012 - jamanetwork.com
Objectives To determine whether patients with myasthenia gravis (MG) have serum
antibodies to lipoprotein-related protein 4 (LRP4), a newly identified receptor for agrin that is …
antibodies to lipoprotein-related protein 4 (LRP4), a newly identified receptor for agrin that is …
[HTML][HTML] Myasthenia gravis: pathogenic effects of autoantibodies on neuromuscular architecture
I Koneczny, R Herbst - Cells, 2019 - mdpi.com
Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction (NMJ).
Autoantibodies target key molecules at the NMJ, such as the nicotinic acetylcholine receptor …
Autoantibodies target key molecules at the NMJ, such as the nicotinic acetylcholine receptor …
Detection and characterization of MuSK antibodies in seronegative myasthenia gravis
J McConville, ME Farrugia, D Beeson… - Annals of …, 2004 - Wiley Online Library
Antibodies to rat muscle specific kinase, MuSK, have recently been identified in some
generalized “seronegative” myasthenia gravis (SNMG) patients, who are often females with …
generalized “seronegative” myasthenia gravis (SNMG) patients, who are often females with …
Antibodies against low-density lipoprotein receptor–related protein 4 induce myasthenia gravis
Myasthenia gravis (MG) is the most common disorder affecting the neuromuscular junction
(NMJ). MG is frequently caused by autoantibodies against acetylcholine receptor (AChR) …
(NMJ). MG is frequently caused by autoantibodies against acetylcholine receptor (AChR) …
Structural basis of agrin–LRP4–MuSK signaling
Synapses are the fundamental units of neural circuits that enable complex behaviors. The
neuromuscular junction (NMJ), a synapse formed between a motoneuron and a muscle …
neuromuscular junction (NMJ), a synapse formed between a motoneuron and a muscle …