Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract infections
and hospitalization in infants under 1 year of age and there is currently no market-approved …

Beyond their role in neutralization, antibodies mediate functions such as phagocytosis,
cytotoxicity, and maintenance of immune homeostasis. Two modifications to the constant …

Natural killer (NK) cells are important effectors of innate immunity playing a key role in the
eradication and clearance of viral infections. Over the recent years, several studies have …

Natural killer (NK) cells play a critical role in viral immunity. In the setting of HIV infection,
epidemiologic and functional evidence support a role for NK cells in both protection from …

There is an urgent need for universal influenza vaccines that can control emerging
pandemic influenza virus threats without the need to generate new vaccines for each strain …

Viruses pose a constant threat to human well-being, necessitating the immune system to
develop robust defenses. Natural killer (NK) cells, which play a crucial role in the immune …

Toll-like receptor (TLR) agonists are potent enhancers of innate antiviral immunity and may
also reverse HIV-1 latency. Therefore, TLR agonists have a potential role in the context of a …

The type I interferon-inducible factor tetherin retains virus particles on the surfaces of cells
infected with vpu-deficient human immunodeficiency virus type 1 (HIV-1). While this …

In the setting of viral challenge, natural killer (NK) cells play an important role as an early
immune responder against infection. During this response, significant changes in the NK cell …

The field of HIV research relies heavily on non-human primates, particularly the members of
the macaque genus, as models for the evaluation of candidate vaccines and monoclonal …