Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives

S Regmi, S Pathak, JO Kim, CS Yong… - European journal of cell …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

Pretreated mesenchymal stem cells and their secretome: enhanced immunotherapeutic strategies

Y Su, C Xu, W Cheng, Y Zhao, L Sui… - International journal of …, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) with self-renewing, multilineage differentiation and
immunomodulatory properties, have been extensively studied in the field of regenerative …

Cell secretome: basic insights and therapeutic opportunities for CNS disorders

AG Pinho, JR Cibrão, NA Silva, S Monteiro… - Pharmaceuticals, 2020 - mdpi.com
Transplantation of stem cells, in particular mesenchymal stem cells (MSCs), stands as a
promising therapy for trauma, stroke or neurodegenerative conditions such as spinal cord or …

Genetic modification and preconditioning strategies to enhance functionality of mesenchymal stromal cells: a clinical perspective

K Moeinabadi-Bidgoli, R Mazloomnejad… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Mesenchymal stromal cell (MSC)-based therapy has generated great hope for
the treatment of various diseases such as myocardial infarction and stroke. Unfortunately …

A review on transcriptional regulation responses to hypoxia in mesenchymal stem cells

N Alijani, B Johari, M Moradi… - Cell Biology …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs), which are known for having therapeutic applications,
reside in stem cell niches where the oxygen concentration is low. At the molecular level, the …

Anti-inflammatory effects of human embryonic stem cell-derived mesenchymal stem cells secretome preconditioned with diazoxide, trimetazidine and MG-132 on LPS …

S Jahandideh, S Khatami, A Eslami Far… - Artificial cells …, 2018 - Taylor & Francis
Systemic inflammatory response syndrome is a complex pathophysiologic and immunologic
response to an insult. Sepsis is a life-threatening condition happening when the body's …

Trimetazidine preconditioning potentiates the effect of mesenchymal stem cells Secretome on the preservation of rat pancreatic islet survival and function In vitro

F Ahmadi, AS Lotfi, M Navaei-Nigjeh… - Applied Biochemistry and …, 2023 - Springer
Islet transplantation offers improved glycemic control in individuals with type 1 diabetes
mellitus. However, in vitro islet culture is associated with islet apoptosis and eventually will …

Investigating the anti‐inflammatory effects of high molecular weight secretions from Limosilactobacillus reuteri PTCC 1655 on LPS‐stimulated PMA‐differentiated THP …

B Johari, F Maghsood, H Madanchi… - Journal of Applied …, 2021 - academic.oup.com
Aims This study was done to investigate the anti‐inflammatory effects of high molecular
weight secretions from Limosilactobacillus reuteri PTCC 1655 probiotic bacteria on …

Studies on conditioned media in human cells: Evaluation using various cell and culture conditions, animal disease models

KC Kim, EJ Lee - Journal of Embryo Transfer, 2018 - koreascience.kr
In the last several decades, cell therapy research has increased worldwide. Many studies
have been conducted on cell therapy, and have revealed that transplanted cells did not …

[PDF][PDF] Comparison of IL-10, TGF-β1, and VEGF Levels in The Secretome of Limbus, Adipose, and Bone Marrow Mesenchymal Stem c3lls

D Hermawan, IK Sudiana, E Komaratih, D Karsari… - academia.edu
Objective: In this study, we investigated whether the levels of IL-10, TGF-1, and VEGF in the
secretome of limbal (LMSCs), adipose (AMSCs), and bone marrow (BMMSCs) …