Estrogen is a fundamental regulator of the metabolic system of the female brain and body.
Within the brain, estrogen regulates glucose transport, aerobic glycolysis, and mitochondrial …

Here we review and extend a new unitary model for the pathophysiology of involutional
osteoporosis that identifies estrogen (E) as the key hormone for maintaining bone mass and …

The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ERα and ERβ,
which differ in the C-terminal ligand-binding domain and in the N-terminal transactivation …

Elwood Jensen and Jack Gorski had spent 10 yr providing experimental evidence to support
the concept of an intracellular “receptor” protein for steroid hormones. Their combined work …

Estrogens and estrogen-like substances are widely distributed in animals and plants, and it
is now clear that estrogens have both nuclear and nonnuclear actions. This review article …

The estrogen receptor (ER) is a ligand-activated enhancer protein that is a member of the
steroid/nuclear receptor superfamily. Two genes encode mammalian ER: ERα and ERβ. ER …

Estrogen Actions in the Central Nervous System* | Endocrine Reviews | Oxford Academic
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Many endocrine disrupting chemicals (EDCs) adversely impact estrogen signaling by
interacting with two estrogen receptors (ERs): ERα and ERβ. Though the receptors have …

Despite the fact that metabolites of alkylphenol ethoxylates (APEO) are classified as
hazardous substances, they continue to be released into the environment from a variety of …

This article reviews evidence for sex differences in vulnerability to addiction with an
emphasis on the neural mechanisms underlying these differences. Sex differences in the …