Nanomaterials are engineered structures with at least one dimension of 100 nanometers or
less. These materials are increasingly being used for commercial purposes such as fillers …

Although humans have been exposed to airborne nanosized particles (NSPs;< 100 nm)
throughout their evolutionary stages, such exposure has increased dramatically over the last …

When a pharmaceutical agent is encapsulated within, or attached to, a polymer or lipid, drug
safety and efficacy can be greatly improved and new therapies are possible. This has …

As the end organ for the treatment of local diseases or as the route of administration for
systemic therapies, the lung is a very attractive target for drug delivery. It provides direct …

Mucus is a selective barrier to particles and molecules, preventing penetration to the
epithelial surface of mucosal tissues. Significant advances in transmucosal drug delivery …

Remarkably, with the exception of anaesthetic gases, the ancient human practice of inhaling
substances into the lungs for systemic effect has only just begun to be adopted by modern …

To date, no effective vaccines or therapies are available against the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), the causative pandemic agent of the coronavirus …

The poor aqueous solubility of many approved drugs and most new chemical entities poses
a challenge to drug delivery scientists working in academic and industrial labs. Despite the …

While all the siRNA drugs on the market target the liver, the lungs offer a variety of currently
undruggable targets which could potentially be treated with RNA therapeutics. Hence, local …

Multiphase chemistry plays a vital role in the Earth system, climate, and health. Chemical
reactions, mass transport, and phase transitions between gases, liquids, and solids are …