Secondary ion mass spectrometry

NP Lockyer, S Aoyagi, JS Fletcher, IS Gilmore… - Nature Reviews …, 2024 - nature.com
Secondary ion mass spectrometry (SIMS) is a technique for chemical analysis and imaging
of solid materials, with applications in many areas of science and technology. It involves …

Emerging computational methods in mass spectrometry imaging

H Hu, J Laskin - Advanced Science, 2022 - Wiley Online Library
Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …

High-throughput nano-DESI mass spectrometry imaging of biological tissues using an integrated microfluidic probe

X Li, H Hu, R Yin, Y Li, X Sun, SK Dey… - Analytical …, 2022 - ACS Publications
Nanospray desorption electrospray mass spectrometry imaging (nano-DESI MSI) enables
quantitative map** of hundreds of molecules in biological samples with minimal sample …

A review on recent machine learning applications for imaging mass spectrometry studies

A Jetybayeva, N Borodinov, AV Ievlev… - Journal of Applied …, 2023 - pubs.aip.org
Imaging mass spectrometry (IMS) is a powerful analytical technique widely used in biology,
chemistry, and materials science fields that continue to expand. IMS provides a qualitative …

Multimodal high-resolution nano-DESI MSI and immunofluorescence imaging reveal molecular signatures of skeletal muscle fiber types

D Unsihuay, H Hu, J Qiu, A Latorre-Palomino… - Chemical …, 2023 - pubs.rsc.org
The skeletal muscle is a highly heterogeneous tissue comprised of different fiber types with
varying contractile and metabolic properties. The complexity in the analysis of skeletal …

Recent advances in mass spectrometry imaging combined with artificial intelligence for spatially clarifying molecular profiles: Toward biomedical applications

H Zhang, J Zhang, C Yuan, D Zhang, D Lu… - TrAC Trends in …, 2024 - Elsevier
Mass spectrometry imaging (MSI) is an intuitive and multidimensional analysis method that
provides spatial information on molecules in tissues or cells; it is widely used in biomedical …

Gábor Transform-Based Signal Isolation, Rapid Deconvolution, and Quantitation of Intact Protein Ions with Mass Spectrometry

KL Meldrum, AK Swansiger, MM Daniels… - Analytical …, 2024 - ACS Publications
High-resolution mass spectrometry (HRMS) is a powerful technique for the characterization
and quantitation of complex biological mixtures, with several applications including clinical …

iSegMSI: an interactive strategy to improve spatial segmentation of mass spectrometry imaging data

L Guo, X Liu, C Zhao, Z Hu, X Xu, KK Cheng… - Analytical …, 2022 - ACS Publications
Spatial segmentation is a critical procedure in mass spectrometry imaging (MSI)-based
biochemical analysis. However, the commonly used unsupervised MSI segmentation …

Analysis of metabolite distribution in rat liver of high-fat model by mass spectrometry imaging

H Mao, W Wang, X **ang, Y Li, J Zhao, Y Huang, S Di… - Metabolites, 2023 - mdpi.com
Hyperlipidemia is a medical condition characterized by elevated levels of blood lipids,
especially triglycerides (TG). However, it remains unclear whether TG levels remain …