Prenatal alcohol exposure is associated to different physical, behavioral, cognitive, and
neurological impairments collectively known as fetal alcohol spectrum disorder. The …

Neurodegenerative disorders like Alzheimer's disease, Huntington's disease, Parkinson's
disease, spinocerebellar ataxias, amyotrophic lateral sclerosis, frontotemporal dementia to …

AimsLifestyle interventions are an important and viable approach for preventing cognitive
deficits. However, the results of studies on alcohol, coffee and tea consumption in relation to …

Rationale Exposure to social defeat (SD) induces a depressive phenotype, increased
ethanol seeking and consumption, accompanied by activation of the neuroinflammatory …

Drug addiction is a chronic and relapsing disorder in which repeated drug exposure
compromises brain neuroplasticity. Brain areas normally involved in learning and goal …

Cognitive reserve (CR) is the capability of an individual to cope with a brain pathology
through compensatory mechanisms developed through cognitive stimulation by mental and …

Chronic alcohol consumption is characterized by disturbances of neuroplasticity. Brain-
derived neurotrophic factor (BDNF) is believed to be critically involved in this process. Here …

Neurotrophins constitute a family of growth factors initially characterized as predominant
mediators of nervous system development, neuronal survival, regeneration and plasticity …

Recent evidence identifies 12 potentially modifiable risk factors for dementia to which 40%
of dementia cases are attributed. While the recognition of these risk factors has paved the …

Background Long-term alcohol exposure is associated with oxidative stress, endoplasmic
reticulum (ER) stress, and neuroinflammation, which may impair cognitive function …