The acquisition of genomic instability is one of the key characteristics of the cancer cell, and
microsatellite instability (MSI) is an important segment of this phenomenon. This review aims …

Accumulating evidence suggests that many classes of DNA repeats exhibit attributes that
distinguish them from other genetic variants, including the fact that they are more liable to …

Autism spectrum disorder (ASD) is an early-onset developmental disorder characterized by
deficits in communication and social interaction and restrictive or repetitive behaviours …

Genomes 5 has been completely revised and updated. It is a thoroughly modern textbook
about genomes and how they are investigated. As with previous Genomes editions …

Short tandem repeats are among the most polymorphic loci in the human genome. These
loci play a role in the etiology of a range of genetic diseases and have been frequently …

Short tandem repeats (STRs) are units of 1–6 bp that repeat in a tandem fashion in DNA.
Along with single nucleotide polymorphisms and large structural variations, they are among …

Short tandem repeats (STRs) have a wide range of applications, including medical genetics,
forensics, and genetic genealogy. High-throughput sequencing (HTS) has the potential to …

Short tandem repeats (STRs) are some of the fastest mutating loci in the genome. Tools for
accurately profiling STRs from high-throughput sequencing data have enabled genome …

Next generation sequencing is revolutionizing molecular ecology by simplifying the
development of molecular genetic markers, including microsatellites. Here, we summarize …

Tandem repeats are genomic elements that are prone to changes in repeat number and are
thus often polymorphic. These sequences are found at a high density at the start of human …