Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis

L Wang, C He - Frontiers in immunology, 2022 - frontiersin.org
Macrophages are the most abundant immune cells within the synovial joints, and also the
main innate immune effector cells triggering the initial inflammatory responses in the …

[HTML][HTML] Progress in polymeric micelles for drug delivery applications

S Kotta, HM Aldawsari, SM Badr-Eldin, AB Nair, K Yt - Pharmaceutics, 2022 - mdpi.com
Polymeric micelles (PMs) have made significant progress in drug delivery applications. A
robust core–shell structure, kinetic stability and the inherent ability to solubilize hydrophobic …

Smart biomaterials for articular cartilage repair and regeneration

Z Gu, J Wang, Y Fu, H Pan, H He… - Advanced Functional …, 2023 - Wiley Online Library
Articular cartilage defects bring about disability and worldwide socioeconomic loss,
therefore, articular cartilage repair and regeneration is recognized as a global issue …

Targeted and responsive biomaterials in osteoarthritis

J Li, H Zhang, Y Han, Y Hu, Z Geng, J Su - Theranostics, 2023 - pmc.ncbi.nlm.nih.gov
Osteoarthritis (OA) is a degenerative disease characterized by loss of articular cartilage and
chronic inflammation, involving multiple cellular dysfunctions and tissue lesions. The non …

[HTML][HTML] Intra-articular nanoparticles based therapies for osteoarthritis and rheumatoid arthritis management

J Wen, H Li, H Dai, S Hua, X Long, H Li, S Ivanovski… - Materials Today Bio, 2023 - Elsevier
Osteoarthritis (OA) and rheumatoid arthritis (RA) are chronic and progressive inflammatory
joint diseases that affect a large population worldwide. Intra-articular administration of …

Anti-inflammatory effects of curcumin in the inflammatory diseases: status, limitations and countermeasures

Y Peng, M Ao, B Dong, Y Jiang, L Yu… - Drug design …, 2021 - Taylor & Francis
Curcumin is a natural compound with great potential for disease treatment. A large number
of studies have proved that curcumin has a variety of biological activities, among which anti …

[HTML][HTML] Flavonoids, anthocyanins, betalains, curcumin, and carotenoids: Sources, classification and enhanced stabilization by encapsulation and adsorption

BL Koop, MN da Silva, FD da Silva… - Food Research …, 2022 - Elsevier
Bioactive compounds have remarkable biological activities for health, nutrition, and food
preservation. However, these compounds are chemically unstable maily when exposure at …

Curcumin-based nanomedicines in the treatment of inflammatory and immunomodulated diseases: an evidence-based comprehensive review

LF Laurindo, GM de Carvalho, B de Oliveira Zanuso… - Pharmaceutics, 2023 - mdpi.com
Curcumin (CUR) is a polyphenol extracted from the rhizome of Curcuma longa that
possesses potent anti-inflammatory and antioxidant potential. Despite CUR's numerous …

Quercetin, epigallocatechin gallate, curcumin, and resveratrol: from dietary sources to human microRNA modulation

E Cione, C La Torre, R Cannataro, MC Caroleo… - Molecules, 2019 - mdpi.com
Epidemiologic studies suggest that dietary polyphenol intake is associated with a lower
incidence of several non-communicable diseases. Although several foods contain complex …

Stimulus‐responsive drug delivery nanoplatforms for osteoarthritis therapy

Q Jiang, S Zhang - Small, 2023 - Wiley Online Library
Osteoarthritis (OA) is one of the most prevalent age‐related degenerative diseases. With an
increasingly aging global population, greater numbers of OA patients are providing clear …