Mitochondria play an essential role in cellular metabolism and generate energy in cells. To
support these functions, several proteins are encoded in the mitochondrial DNA (mtDNA) …

How mitochondria came to reside within the cytosol of their host has been debated for 50
years. Though current data indicate that the last eukaryote common ancestor possessed …

Discoveries of diverse microbial eukaryotes and their inclusion in comprehensive
phylogenomic analyses have crucially re-shaped the eukaryotic tree of life in the 21st …

Mitochondria are essential organelles of eukaryotic cells. They consist of hundreds of
different proteins that exhibit crucial activities in respiration, catabolic metabolism and the …

Many anaerobic microbial parasites possess highly modified mitochondria known as
mitochondrion-related organelles (MROs). The best-studied of these are the …

Two eukaryotic compartments are of endosymbiotic origin, the mitochondrion and plastid.
These organelles need to import hundreds of proteins from the cytosol. The import …

The microaerophilic protist parasite Trichomonas vaginalis is occurring globally and causes
infections in the urogenital tract in humans, a condition termed trichomoniasis. In fact …

Blastocystis is the most prevalent microbial eukaryote in the human and animal gut, yet its
role as commensal or parasite is still under debate. Blastocystis has clearly undergone …

Metamonads are a diverse group of heterotrophic microbial eukaryotes adapted to living in
hypoxic environments. All metamonads but one harbour metabolically altered …

The establishment of the mitochondrion is seen as a transformational step in the origin of
eukaryotes. With the mitochondrion came bioenergetic freedom to explore novel …