Curcumin: the Indian solid gold

BB Aggarwal, C Sundaram, N Malani… - The molecular targets and …, 2007 - Springer
Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in
the Indian subcontinent, not only for health care but also for the preservation of food and as …

Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature

P Anand, SG Thomas, AB Kunnumakkara… - Biochemical …, 2008 - Elsevier
Curcumin, a yellow pigment present in the Indian spice turmeric (associated with curry
powder), has been linked with suppression of inflammation; angiogenesis; tumorigenesis; …

Tailored Palladium Catalysts for Selective Synthesis of Conjugated Enynes by Monocarbonylation of 1, 3‐Diynes

J Liu, J Yang, C Schneider, R Franke… - Angewandte Chemie …, 2020 - Wiley Online Library
For the first time, the monoalkoxycarbonylation of easily available 1, 3‐diynes to give
synthetically useful conjugated enynes has been realized. Key to success was the design …

Anticancer curcumin: natural analogues and structure-activity relationship

AP Gupta, S Khan, MM Manzoor, AK Yadav… - Studies in natural …, 2017 - Elsevier
Cancers have been found to be the leading causes of death worldwide, with 8.2 million
people dying in 2012 and approximately 14 million new cases reported. These cases are …

An overview of structure–activity relationship studies of curcumin analogs as antioxidant and anti-inflammatory agents

L Arshad, MA Haque, SN Abbas Bukhari… - Future medicinal …, 2017 - Taylor & Francis
Curcumin, extracted mainly from Curcuma longa rhizomes, has been reported to possess
potent anti-inflammatory and anti-oxidant activities. Although safe at higher doses and …

Synthesis and antioxidant activity of curcumin analogs

QT Zheng, ZH Yang, LY Yu, YY Ren… - Journal of Asian …, 2017 - Taylor & Francis
Numerous biological activities including antioxidant, antitumor, anti-inflammation, and
antivirus of the natural product curcumin were reported. However, the clinical application of it …

Substituted thiazoles V. Synthesis and antitumor activity of novel thiazolo [2, 3-b] quinazoline and pyrido [4, 3-d] thiazolo [3, 2-a] pyrimidine analogues

FAM Al-Omary, GS Hassan, SM El-Messery… - European journal of …, 2012 - Elsevier
A novel series of thiazolo [2, 3-b] quinazoline (14–23, 26 and 27), and pyrido [4, 3-d] thiazolo
[3, 2-a] pyrimidine (34–43, 45 and 46) analogues were designed and synthesized. The …

Immunosuppressive effects of natural α, β-unsaturated carbonyl-based compounds, and their analogs and derivatives, on immune cells: a review

L Arshad, I Jantan, SNA Bukhari… - Frontiers in …, 2017 - frontiersin.org
The immune system is complex and pervasive as it functions to prevent or limit infections in
the human body. In a healthy organism, the immune system and the redox balance of …

Promising curcumin-based drug design: mono-carbonyl analogues of curcumin (MACs)

C Zhao, Z Liu, G Liang - Current pharmaceutical design, 2013 - ingentaconnect.com
Curcumin exhibits a surprisingly wide range of chemo-preventive and chemo-therapeutic
activities. Curcumin has undergone more than 40 clinical trials for the treatment of …

Preliminary Investigation Into the Antidepressant Effects of a Novel Curcumin Analogue (CACN136) In Vitro and In Vivo

J Chen, Y Wei, N Li, C Pi, W Zhao, Y Zhong, W Li… - Molecular …, 2024 - Springer
The aim of this study was to develop a novel antidepressant with high activity. Based on the
findings of molecular docking, eight novel curcumin analogues were evaluated in vitro to …