Composite biopolymers for bone regeneration enhancement in bony defects

K Jahan, M Tabrizian - Biomaterials science, 2016 - pubs.rsc.org
For the past century, various biomaterials have been used in the treatment of bone defects
and fractures. Their role as potential substitutes for human bone grafts increases as donors …

Biological aspects of segmental bone defects management

I Dumic-Cule, M Pecina, M Jelic, M Jankolija… - International …, 2015 - Springer
Segmental bone defect management is among the most demanding issues in orthopaedics
and there is a great medical need for establishing an appropriate treatment option. Tissue …

Nanomechanical map** of hard tissues by atomic force microscopy: An application to cortical bone

M Bontempi, F Salamanna, R Capozza, A Visani… - Materials, 2022 - mdpi.com
Force map** of biological tissues via atomic force microscopy (AFM) probes the
mechanical properties of samples within a given topography, revealing the interplay …

Addition of mesenchymal stem cells to autologous platelet-enhanced fibrin scaffolds in chondral defects: does it enhance repair?

LR Goodrich, AC Chen, NM Werpy, AA Williams… - JBJS, 2016 - journals.lww.com
Background: The chondrogenic potential of culture-expanded bone-marrow-derived
mesenchymal stem cells (BMDMSCs) is well described. Numerous studies have also shown …

BEM evaluation of surface octahedral strains and internal strain gradients in 3D-printed scaffolds used for bone tissue regeneration

TV Gortsas, SV Tsinopoulos, E Polyzos, L Pyl… - Journal of the …, 2022 - Elsevier
Most of the mechnoregulatory computational models appearing so far in tissue engineering
for bone healing predictions, utilize as regulators for cell differentiation mainly the octahedral …

The role of three‐dimensional scaffolds in treating long bone defects: evidence from preclinical and clinical literature—a systematic review

A Roffi, GS Krishnakumar, N Gostynska… - BioMed Research …, 2017 - Wiley Online Library
Long bone defects represent a clinical challenge. Bone tissue engineering (BTE) has been
developed to overcome problems associated with conventional methods. The aim of this …

Layer-by-layer bioassembly of cellularized polylactic acid porous membranes for bone tissue engineering

V Guduric, C Metz, R Siadous, R Bareille… - Journal of Materials …, 2017 - Springer
The conventional tissue engineering is based on seeding of macroporous scaffold on its
surface (“top–down” approach). The main limitation is poor cell viability in the middle of the …

Mechanical deviation in 3D-Printed PLA bone scaffolds during biodegradation

S Senaysoy, R Ilhan, H Lekesiz - Computers in Biology and Medicine, 2024 - Elsevier
Large or carcinogenic bone defects may require a challenging bone tissue scaffold design
ensuring a proper mechanobiological setting. Porosity and biodegradation rate are the key …

[HTML][HTML] Polycaprolactone for Hard Tissue Regeneration: Scaffold Design and In Vivo Implications

F Ramírez-Ruiz, I Núñez-Tapia, MC Piña-Barba… - Bioengineering, 2025 - mdpi.com
In the last thirty years, tissue engineering (TI) has emerged as an alternative method to
regenerate tissues and organs and restore their function by implanting specific lineage cells …

Polymer based scaffolds for tissue regeneration by stereolithography

A Ronca, L Ambrosio - Advanced Biomaterials and Devices in …, 2017 - cyberleninka.ru
Stereolithography is a rapid prototy** technique, introduced in the 1980s, that enables the
realization of complex 3D structures for tissue engineering directly from a computer model …