Atherosclerosis is an inflammatory disease of the large arteries that is the major cause of
cardiovascular disease (CVD) and stroke. Here, we review the current understanding of the …

Atherosclerosis is a chronic inflammatory vascular disease and the predominant cause of
heart attack and ischemic stroke. Despite the well-known sexual dimorphism in the …

An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology
and has the potential to be used in medical and pharmaceutical research to obtain results …

Animal studies are a foundation for defining mechanisms of atherosclerosis and potential
targets of drugs to prevent lesion development or reverse the disease. In the current …

Wu et al The RAS and Cardiovascular Functions e109 homocysteine decreased
antihypertensive effect of enalapril, an ACE inhibitor, in chronic hypertensive patients. 61 …

Atherosclerotic plaques impair vascular function and can lead to arterial obstruction and
tissue ischaemia. Rupture of an atherosclerotic plaque within a coronary artery can result in …

Cardiovascular calcification is a health disorder with increasing prevalence and high
morbidity and mortality. The only available therapeutic options for calcific vascular and …

Efficient delivery of specific cargos in vivo poses a major challenge to the secretory pathway,
which shuttles products encoded by∼ 30% of the genome. Newly synthesized protein and …

Objective: Endothelial Cav-1 (caveolin-1) expression plays a relevant role during
atherogenesis by controlling NO production, vascular inflammation, LDL (low-density …