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Semaphorins and their signaling mechanisms
LT Alto, JR Terman - Semaphorin Signaling: Methods and Protocols, 2017 - Springer
Semaphorins are extracellular signaling proteins that are essential for the development and
maintenance of many organs and tissues. The more than 20-member semaphorin protein …
maintenance of many organs and tissues. The more than 20-member semaphorin protein …
Neurobiological bases of autism–epilepsy comorbidity: a focus on excitation/inhibition imbalance
Y Bozzi, G Provenzano… - European Journal of …, 2018 - Wiley Online Library
Autism spectrum disorders (ASD) and epilepsy are common neurological diseases of
childhood, with an estimated incidence of approximately 0.5–1% of the worldwide …
childhood, with an estimated incidence of approximately 0.5–1% of the worldwide …
Semaphorins in adult nervous system plasticity and disease
D Carulli, F De Winter, J Verhaagen - Frontiers in synaptic …, 2021 - frontiersin.org
Semaphorins, originally discovered as guidance cues for develo** axons, are involved in
many processes that shape the nervous system during development, from neuronal …
many processes that shape the nervous system during development, from neuronal …
De novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP
Individuals with severe, sporadic disorders of infantile onset represent an important class of
disease for which discovery of the underlying genetic architecture is not amenable to …
disease for which discovery of the underlying genetic architecture is not amenable to …
Common circuit defect of excitatory-inhibitory balance in mouse models of autism
One unifying explanation for the complexity of Autism Spectrum Disorders (ASD) may lie in
the disruption of excitatory/inhibitory (E/I) circuit balance during critical periods of …
the disruption of excitatory/inhibitory (E/I) circuit balance during critical periods of …
Biology of GDNF and its receptors—relevance for disorders of the central nervous system
A targeted effort to identify novel neurotrophic factors for midbrain dopaminergic neurons
resulted in the isolation of GDNF (glial cell line-derived neurotrophic factor) from the …
resulted in the isolation of GDNF (glial cell line-derived neurotrophic factor) from the …
Lack of parvalbumin in mice leads to behavioral deficits relevant to all human autism core symptoms and related neural morphofunctional abnormalities
Gene mutations and gene copy number variants are associated with autism spectrum
disorders (ASDs). Affected gene products are often part of signaling networks implicated in …
disorders (ASDs). Affected gene products are often part of signaling networks implicated in …
Cellular and molecular mechanisms controlling the migration of neocortical interneurons
The discovery, approximately 15 years ago, that cortical GABA ergic interneurons originate
outside the pallium has revolutionized our understanding of the development of the cerebral …
outside the pallium has revolutionized our understanding of the development of the cerebral …
Guidance molecules in synapse formation and plasticity
A major goal of modern neuroscience research is to understand the cellular and molecular
processes that control the formation, function, and remodeling of chemical synapses. In this …
processes that control the formation, function, and remodeling of chemical synapses. In this …
Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions
Plexin transmembrane receptors and their semaphorin ligands, as well as their co-receptors
(Neuropilin, Integrin, VEGFR2, ErbB2, and Met kinase) are emerging as key regulatory …
(Neuropilin, Integrin, VEGFR2, ErbB2, and Met kinase) are emerging as key regulatory …