Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?

SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022‏ - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall, characterized by the
formation of plaques containing lipid, connective tissue and immune cells in the intima of …

Heart disease and stroke statistics—2018 update: a report from the American Heart Association

EJ Benjamin, SS Virani, CW Callaway… - Circulation, 2018‏ - ahajournals.org
Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart
Association | Circulation Skip to main content Become a member Volunteer Donate centennial Go …

UK Biobank release and systematic evaluation of optimised polygenic risk scores for 53 diseases and quantitative traits

DJ Thompson, D Wells, S Selzam, I Peneva, R Moore… - MedRxiv, 2022‏ - medrxiv.org
We present and assess the UK Biobank (UKB) Polygenic Risk Score (PRS) Release, a set of
PRSs for 28 diseases and 25 quantitative traits being made available on the individuals in …

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

R Malik, G Chauhan, M Traylor, M Sargurupremraj… - Nature …, 2018‏ - nature.com
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …

Heart disease and stroke statistics—2017 update: a report from the American Heart Association

EJ Benjamin, MJ Blaha, SE Chiuve, M Cushman… - circulation, 2017‏ - ahajournals.org
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke

J Montaner, L Ramiro, A Simats, S Tiedt… - Nature Reviews …, 2020‏ - nature.com
Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …

A systematic evaluation of the performance and properties of the UK Biobank Polygenic Risk Score (PRS) Release

DJ Thompson, D Wells, S Selzam, I Peneva, R Moore… - Plos one, 2024‏ - journals.plos.org
We assess the UK Biobank (UKB) Polygenic Risk Score (PRS) Release, a set of PRSs for 28
diseases and 25 quantitative traits that has been made available on the individuals in UKB …

Heart disease and stroke statistics—2016 update: a report from the American Heart Association

D Mozaffarian, EJ Benjamin, AS Go, DK Arnett… - circulation, 2016‏ - ahajournals.org
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

[HTML][HTML] Guidelines for the primary prevention of stroke

JF Meschia, C Bushnell, B Boden-Albala, LT Braun… - Stroke, 2014‏ - journals.lww.com
The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …

Heart disease and stroke statistics—2014 update: a report from the American Heart Association

AS Go, D Mozaffarian, VL Roger, EJ Benjamin… - circulation, 2014‏ - ahajournals.org
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …