Leishmania species: A narrative review on surface proteins with structural aspects involved in host–pathogen interaction

RS Kaushal, N Naik, M Prajapati… - Chemical Biology & …, 2023 - Wiley Online Library
In tropical and subtropical regions of the world, leishmaniasis is endemic and causes a
range of clinical symptoms in people, from severe tegumentary forms (such as cutaneous …

Cell‐membrane‐display nanotechnology

Y Wang, P Zhang, Y Wei, K Shen, L **ao… - Advanced …, 2021 - Wiley Online Library
Advances in material science have set the stage for nanoparticle‐based research with
potent applications for the diagnosis, bioimaging, and precise treatment of diseases. Despite …

Interaction of antimicrobial peptides with model membranes: a perspective towards new antibiotics

S Karmakar, S Das, KK Banerjee - The European Physical Journal Special …, 2024 - Springer
Antimicrobial peptides (AMPs), found in both animals and plants, are used to fend off a wide
variety of invading pathogens, such as bacteria, fungi, protozoa, viruses, etc. Their …

Linking membrane fluidity with defective antigen presentation in leishmaniasis

S Pradhan, S Ghosh, S Hussain, J Paul… - Parasite …, 2021 - Wiley Online Library
Hampering‐surface presentation of immunogenic peptides by class I/II MHCs is a key
strategy opted by several intracellular protozoan pathogens including Leishmania to escape …

Leishmania protein KMP-11 modulates cholesterol transport and membrane fluidity to facilitate host cell invasion

A Sannigrahi, S Ghosh, S Pradhan, P Jana… - EMBO …, 2024 - embopress.org
The first step of successful infection by any intracellular pathogen relies on its ability to
invade its host cell membrane. However, the detailed structural and molecular …

An evidence of pores in phospholipid membrane induced by an antimicrobial peptide NK-2

A Halder, S Karmakar - Biophysical Chemistry, 2022 - Elsevier
NK-2, a peptide derived from a cationic core region of NK-lysin, has emerged as a promising
candidate for new antibiotics. In contrast to classical antibiotics, antimicrobial peptides target …

Studies of Protein Phase Separation Using Leishmania Kinetoplastid Membrane Protein-11

R Roy, D Sanyal, S Roychowdhury… - The Journal of …, 2025 - ACS Publications
Despite the significant understanding of phase separation in proteins with intrinsically
disordered regions, a considerable percentage of proteins without such regions also …

Membrane composition and lipid to protein ratio modulate amyloid kinetics of yeast prion protein

A Bandyopadhyay, A Sannigrahi… - RSC Chemical …, 2021 - pubs.rsc.org
Understanding of prion aggregation in a membrane environment may help to ameliorate
neurodegenerative complications caused by the amyloid forms of prions. Here, we …

Mechanism of host cell invasion by Leishmania through KMP-11 mediated cholesterol-transport and membrane phase transition

A Sannigrahi, S Ghosh, S Pradhan, P Jana, JJ Jawed… - bioRxiv, 2024 - biorxiv.org
The first step of successful infection by any intracellular pathogen relies on its ability to
invade its host cell membrane. However, the detailed structural and molecular …

Leishmanial apolipoprotein AI expression: a possible strategy used by the parasite to evade the host's immune response

K Kalantar, R Manzano-Román, E Ghani… - Future …, 2021 - Taylor & Francis
Apolipoprotein AI (apo AI) represents the main component of the Trypanosome lytic factor
(TLF) which contributes to the host innate immunity against Trypanosoma and Leishmania …