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Marine natural products
Covering: January to December 2017 This review covers the literature published in 2017 for
marine natural products (MNPs), with 740 citations (723 for the period January to December …
marine natural products (MNPs), with 740 citations (723 for the period January to December …
Potential role of marine bioactive compounds in cancer signaling pathways: A review
S Manoharan, E Perumal - European Journal of Pharmacology, 2022 - Elsevier
Cancer is characterized by alterations that cause the over-proliferation of cells and
hyperactivation of signaling pathways. Alterations of signaling molecules dysregulate …
hyperactivation of signaling pathways. Alterations of signaling molecules dysregulate …
[HTML][HTML] Lanatoside C induces G2/M cell cycle arrest and suppresses cancer cell growth by attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR signaling …
Cardiac glycosides (CGs) are a diverse family of naturally derived compounds having a
steroid and glycone moiety in their structures. CG molecules inhibit the α-subunit of …
steroid and glycone moiety in their structures. CG molecules inhibit the α-subunit of …
[HTML][HTML] The effect of encapsulated apigenin nanoparticles on HePG-2 cells through regulation of P53
Apigenin (Ap) is one of the most important natural flavonoids that has potent anticancer
activity. This study was designed, for the first time, to load Ap into chitosan to improve its …
activity. This study was designed, for the first time, to load Ap into chitosan to improve its …
Apigetrin induces extrinsic apoptosis, autophagy and G2/M phase cell cycle arrest through PI3K/AKT/mTOR pathway in AGS human gastric cancer cell
SM Kim, P Vetrivel, SE Ha, HH Kim, JA Kim… - The Journal of Nutritional …, 2020 - Elsevier
Apigetrin is a flavonoid glycoside phytonutrient derived from fruits and vegetables that is well
known for a variety of biological activities such as antioxidant and anti-inflammatory …
known for a variety of biological activities such as antioxidant and anti-inflammatory …
Anticancer molecular mechanism of protocatechuic acid loaded on folate coated functionalized graphene oxide nanocomposite delivery system in human …
Liver cancer is listed as the fifth-ranked cancer, responsible for 9.1% of all cancer deaths
globally due to its assertive nature and poor survival rate. To overcome this obstacle, efforts …
globally due to its assertive nature and poor survival rate. To overcome this obstacle, efforts …
[HTML][HTML] Cyclobutane pyrimidine dimers from UVB exposure induce a hypermetabolic state in keratinocytes via mitochondrial oxidative stress
Ultraviolet B radiation (UVB) is an environmental complete carcinogen, which induces and
promotes keratinocyte carcinomas, the most common human malignancies. UVB induces …
promotes keratinocyte carcinomas, the most common human malignancies. UVB induces …
Sinularin selectively kills breast cancer cells showing G2/M arrest, apoptosis, and oxidative DNA damage
HW Huang, JY Tang, F Ou-Yang, HR Wang, PY Guan… - Molecules, 2018 - mdpi.com
The natural compound sinularin, isolated from marine soft corals, is antiproliferative against
several cancers, but its possible selective killing effect has rarely been investigated. This …
several cancers, but its possible selective killing effect has rarely been investigated. This …
Simvastatin-loaded gelatin-capped polycaprolactone nanoparticles for the post-operative management of breast cancer
Minimal residual disease at the tumor site after surgical ablation is a major cause for tumor
recurrence and metastasis. The tropism of circulating tumor cells towards injured areas …
recurrence and metastasis. The tropism of circulating tumor cells towards injured areas …
[HTML][HTML] Sinularin induces oxidative stress-mediated apoptosis and mitochondrial dysfunction, and inhibits angiogenesis in glioblastoma cells
Glioblastoma multiforme (GBM) is a cancer of largely unknown cause that leads to a 5-year
survival rate of approximately 7% in the United States. Current treatment strategies are not …
survival rate of approximately 7% in the United States. Current treatment strategies are not …