Marine natural products

AR Carroll, BR Copp, RA Davis, RA Keyzers… - Natural product …, 2019 - pubs.rsc.org
Covering: January to December 2017 This review covers the literature published in 2017 for
marine natural products (MNPs), with 740 citations (723 for the period January to December …

Potential role of marine bioactive compounds in cancer signaling pathways: A review

S Manoharan, E Perumal - European Journal of Pharmacology, 2022 - Elsevier
Cancer is characterized by alterations that cause the over-proliferation of cells and
hyperactivation of signaling pathways. Alterations of signaling molecules dysregulate …

[HTML][HTML] The effect of encapsulated apigenin nanoparticles on HePG-2 cells through regulation of P53

MM Mabrouk Zayed, HA Sahyon, NAN Hanafy… - Pharmaceutics, 2022 - mdpi.com
Apigenin (Ap) is one of the most important natural flavonoids that has potent anticancer
activity. This study was designed, for the first time, to load Ap into chitosan to improve its …

Apigetrin induces extrinsic apoptosis, autophagy and G2/M phase cell cycle arrest through PI3K/AKT/mTOR pathway in AGS human gastric cancer cell

SM Kim, P Vetrivel, SE Ha, HH Kim, JA Kim… - The Journal of Nutritional …, 2020 - Elsevier
Apigetrin is a flavonoid glycoside phytonutrient derived from fruits and vegetables that is well
known for a variety of biological activities such as antioxidant and anti-inflammatory …

Sinularin selectively kills breast cancer cells showing G2/M arrest, apoptosis, and oxidative DNA damage

HW Huang, JY Tang, F Ou-Yang, HR Wang, PY Guan… - Molecules, 2018 - mdpi.com
The natural compound sinularin, isolated from marine soft corals, is antiproliferative against
several cancers, but its possible selective killing effect has rarely been investigated. This …

Simvastatin-loaded gelatin-capped polycaprolactone nanoparticles for the post-operative management of breast cancer

P Famta, S Shah, DA Srinivasarao, A Sharma… - Journal of Drug Delivery …, 2024 - Elsevier
Minimal residual disease at the tumor site after surgical ablation is a major cause for tumor
recurrence and metastasis. The tropism of circulating tumor cells towards injured areas …

[HTML][HTML] Sinularin induces oxidative stress-mediated apoptosis and mitochondrial dysfunction, and inhibits angiogenesis in glioblastoma cells

SY Hsu, ZH Wen, PC Shih, HM Kuo, SC Lin, HT Liu… - Antioxidants, 2022 - mdpi.com
Glioblastoma multiforme (GBM) is a cancer of largely unknown cause that leads to a 5-year
survival rate of approximately 7% in the United States. Current treatment strategies are not …