Recent advances in super-resolution optical imaging based on aggregation-induced emission

FY Zhu, LJ Mei, R Tian, C Li, YL Wang… - Chemical Society …, 2024 - pubs.rsc.org
Super-resolution imaging has rapidly emerged as an optical microscopy technique, offering
advantages of high optical resolution over the past two decades; achieving improved …

Single-molecule localization microscopy

M Lelek, MT Gyparaki, G Beliu, F Schueder… - Nature reviews …, 2021 - nature.com
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …

Molecular photoswitches in aqueous environments

J Volarić, W Szymanski, NA Simeth… - Chemical Society …, 2021 - pubs.rsc.org
Molecular photoswitches enable dynamic control of processes with high spatiotemporal
precision, using light as external stimulus, and hence are ideal tools for different research …

Democratising deep learning for microscopy with ZeroCostDL4Mic

L von Chamier, RF Laine, J Jukkala, C Spahn… - Nature …, 2021 - nature.com
Deep Learning (DL) methods are powerful analytical tools for microscopy and can
outperform conventional image processing pipelines. Despite the enthusiasm and …

An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity

NE Weisser, M Sanches, E Escobar-Cabrera… - Nature …, 2023 - nature.com
Human epidermal growth factor receptor 2 (HER2) is a receptor tyrosine kinase that plays an
oncogenic role in breast, gastric and other solid tumors. However, anti-HER2 therapies are …

Super-resolution microscopy for structural cell biology

S Liu, P Hoess, J Ries - Annual Review of Biophysics, 2022 - annualreviews.org
Super-resolution microscopy techniques, and specifically single-molecule localization
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …

Fluorescence nanoscopy in cell biology

SJ Sahl, SW Hell, S Jakobs - Nature reviews Molecular cell biology, 2017 - nature.com
Fluorescence nanoscopy uniquely combines minimally invasive optical access to the
internal nanoscale structure and dynamics of cells and tissues with molecular detection …

Expansion microscopy: principles and uses in biological research

AT Wassie, Y Zhao, ES Boyden - Nature methods, 2019 - nature.com
Many biological investigations require 3D imaging of cells or tissues with nanoscale spatial
resolution. We recently discovered that preserved biological specimens can be physically …

Super-resolution microscopy with DNA-PAINT

J Schnitzbauer, MT Strauss, T Schlichthaerle… - Nature protocols, 2017 - nature.com
Super-resolution techniques have begun to transform biological and biomedical research by
allowing researchers to observe structures well below the classic diffraction limit of light …