Dynamic nucleolar phase separation influenced by non-canonical function of LIN28A instructs pluripotent stem cell fate decisions
T Tan, B Gao, H Yu, H Pan, Z Sun, A Lei… - Nature …, 2024 - nature.com
LIN28A is important in somatic reprogramming and pluripotency regulation. Although
previous studies addressed that LIN28A can repress let-7 microRNA maturation in the …
previous studies addressed that LIN28A can repress let-7 microRNA maturation in the …
Nephron-Specific Lin28A Overexpression Triggers Severe Inflammatory Response and Kidney Damage
A Futorian, L Armon, HW Ben-Asher… - International …, 2024 - pmc.ncbi.nlm.nih.gov
The RNA-binding proteins LIN28A and LIN28B contribute to a variety of developmental
biological processes. Dysregulation of Lin28A and Lin28B expression is associated with …
biological processes. Dysregulation of Lin28A and Lin28B expression is associated with …
Lin28a maintains a subset of adult muscle stem cells in an embryonic-like state
P Wang, X Liu, Z Yao, Y Chen, L Luo, K Liang… - Cell Research, 2023 - nature.com
During homeostasis and after injury, adult muscle stem cells (MuSCs) activate to mediate
muscle regeneration. However, much remains unclear regarding the heterogeneous …
muscle regeneration. However, much remains unclear regarding the heterogeneous …
Enhanced protein synthesis is a defining requirement for neonatal B cell development
H Åkerstrand, E Boldrin, G Montano, S Vanhee… - Frontiers in …, 2023 - frontiersin.org
The LIN28B RNA binding protein exhibits an ontogenically restricted expression pattern and
is a key molecular regulator of fetal and neonatal B lymphopoiesis. It enhances the positive …
is a key molecular regulator of fetal and neonatal B lymphopoiesis. It enhances the positive …
Lin28a rejuvenates muscle stem cells via mitochondrial optimization
P Wang, X Liu, JH Elwin Tan, MW Jason Chua… - bioRxiv, 2021 - biorxiv.org
The well-conserved correlation between juvenility and tissue regeneration was first
discussed by Charles Darwin. Ectopic Lin28 is known to play an important role in somatic …
discussed by Charles Darwin. Ectopic Lin28 is known to play an important role in somatic …
[PDF][PDF] Lin28b regulation of early-life B lymphopoiesis. A model system to study how self-reactive B cells develop in early life.
H Åkerstrand - 2023 - portal.research.lu.se
Antibody secretion by the B cell is an integral part of our immune system. Since our body
contains millions of B cells expressing unique antibodies, together they afford an impressive …
contains millions of B cells expressing unique antibodies, together they afford an impressive …