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Oxidative stress‐related mechanisms in schizophrenia pathogenesis and new treatment perspectives
EA Ermakov, EM Dmitrieva… - Oxidative Medicine …, 2021 - Wiley Online Library
Schizophrenia is recognized to be a highly heterogeneous disease at various levels, from
genetics to clinical manifestations and treatment sensitivity. This heterogeneity is also …
genetics to clinical manifestations and treatment sensitivity. This heterogeneity is also …
Clozapine's multiple cellular mechanisms: What do we know after more than fifty years? A systematic review and critical assessment of translational mechanisms …
A de Bartolomeis, L Vellucci, A Barone… - Pharmacology & …, 2022 - Elsevier
Almost fifty years after its first introduction into clinical care, clozapine remains the only
evidence-based pharmacological option for treatment-resistant schizophrenia (TRS), which …
evidence-based pharmacological option for treatment-resistant schizophrenia (TRS), which …
[HTML][HTML] Endocrine disruption and obesity: A current review on environmental obesogens
Obesity represents an important public health concern because it substantially increases the
risk of multiple chronic diseases and thereby contributing to a decline in both quality of life …
risk of multiple chronic diseases and thereby contributing to a decline in both quality of life …
Evaluation of antioxidant enzymes activities and lipid peroxidation in schizophrenic patients treated with typical and atypical antipsychotics
Studies performed in schizophrenia patients have generally suggested the presence of a
compromised antioxidant system, but this is not always consistent with specific observed …
compromised antioxidant system, but this is not always consistent with specific observed …
Atypical antipsychotics-induced metabolic syndrome and nonalcoholic fatty liver disease: a critical review
H Xu, X Zhuang - Neuropsychiatric disease and treatment, 2019 - Taylor & Francis
The atypical antipsychotics (AAPs) have been used as first-line drugs in psychiatric practice
for a wide range of psychotic disorders, including schizophrenia and bipolar mania. While …
for a wide range of psychotic disorders, including schizophrenia and bipolar mania. While …
Oxidation-reduction mechanisms in psychiatric disorders: A novel target for pharmacological intervention
While neurotransmitter dysfunction represents a key component in mental illnesses, there is
now a wide agreement for a central pathophysiological hub that includes hormones …
now a wide agreement for a central pathophysiological hub that includes hormones …
Antipsychotics-induced metabolic alterations: focus on adipose tissue and molecular mechanisms
P Gonçalves, JR Araújo, F Martel - European Neuropsychopharmacology, 2015 - Elsevier
The use of antipsychotic drugs for the treatment of mood disorders and psychosis has
increased dramatically over the last decade. Despite its consumption being associated with …
increased dramatically over the last decade. Despite its consumption being associated with …
Role of rutin nanoemulsion in ameliorating oxidative stress: pharmacokinetic and pharmacodynamics studies
Parkinson's disease is caused due to free radical generation in dopamine neurons leading
to oxidative stress induced damage. The aim of this work was to ameliorate the free radical …
to oxidative stress induced damage. The aim of this work was to ameliorate the free radical …
Berberine ameliorate haloperidol and 3-Nitropropionic acid-induced neurotoxicity in rats
Berberine due to its antioxidant properties, has been used around the globe significantly to
treat several brain disorders. Also, oxidative stress is a pathological hallmark in …
treat several brain disorders. Also, oxidative stress is a pathological hallmark in …
Clozapine-induced mitochondria alterations and inflammation in brain and insulin-responsive cells
V Contreras-Shannon, DL Heart, RM Paredes… - PloS one, 2013 - journals.plos.org
Background Metabolic syndrome (MetS) is a constellation of factors including abdominal
obesity, hyperglycemia, dyslipidemias, and hypertension that increase morbidity and …
obesity, hyperglycemia, dyslipidemias, and hypertension that increase morbidity and …