Antimicrobial ionic liquid‐based materials for biomedical applications
Excessive and unwarranted administration of antibiotics has invigorated the evolution of
multidrug‐resistant microbes. There is, therefore, an urgent need for advanced active …
multidrug‐resistant microbes. There is, therefore, an urgent need for advanced active …
The medicinal chemistry of ferrocene and its derivatives
Ferrocene derivatives have attracted significant interest as anticancer, antibacterial,
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …
Has ferrocene really delivered its role in accentuating the bioactivity of organic scaffolds?
Ferrocene is an important structural core in bioorganometallic chemistry because of its
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …
Metal complexes, an untapped source of antibiotic potential?
A Frei - Antibiotics, 2020 - mdpi.com
With the widespread rise of antimicrobial resistance, most traditional sources for new drug
compounds have been explored intensively for new classes of antibiotics. Meanwhile, metal …
compounds have been explored intensively for new classes of antibiotics. Meanwhile, metal …
The potential of organometallic complexes in medicinal chemistry
Organometallic complexes have unique physico-chemical properties, which have been
widely used in homogenous catalysis, for example, for the synthesis of lead compounds and …
widely used in homogenous catalysis, for example, for the synthesis of lead compounds and …
Ferrocene-based drugs, delivery nanomaterials and fenton mechanism: state of the art, recent developments and prospects
Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …
bioinorganic drugs to cure cancers and various other diseases. Following several …
Small organometallic compounds as antibacterial agents
The emergence of bacterial resistance to commercial antibiotics is an issue of global
importance. During the last two decades, the number of antibacterial agents that have been …
importance. During the last two decades, the number of antibacterial agents that have been …
Ferrocene derivatives as anti-infective agents
BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …
Bio‐Organometallic Derivatives of Antibacterial Drugs
MA Sierra, L Casarrubios… - Chemistry–A European …, 2019 - Wiley Online Library
Overuse and misuse of antibacterial drugs has resulted in bacteria resistance and in an
increase in mortality rates due to bacterial infections. Therefore, there is an imperative …
increase in mortality rates due to bacterial infections. Therefore, there is an imperative …
FerriIridium: A Lysosome‐Targeting Iron (III)‐Activated Iridium (III) Prodrug for Chemotherapy in Gastric Cancer Cells
Reported is the FeIII‐activated lysosome‐targeting prodrug FerriIridium for gastric cancer
theranostics. It contains a meta‐imino catechol group that can selectively bond to, and be …
theranostics. It contains a meta‐imino catechol group that can selectively bond to, and be …