Antimicrobial ionic liquid‐based materials for biomedical applications

N Nikfarjam, M Ghomi, T Agarwal… - Advanced Functional …, 2021 - Wiley Online Library
Excessive and unwarranted administration of antibiotics has invigorated the evolution of
multidrug‐resistant microbes. There is, therefore, an urgent need for advanced active …

The medicinal chemistry of ferrocene and its derivatives

M Patra, G Gasser - Nature Reviews Chemistry, 2017 - nature.com
Ferrocene derivatives have attracted significant interest as anticancer, antibacterial,
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …

Has ferrocene really delivered its role in accentuating the bioactivity of organic scaffolds?

B Sharma, V Kumar - Journal of medicinal chemistry, 2021 - ACS Publications
Ferrocene is an important structural core in bioorganometallic chemistry because of its
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …

Metal complexes, an untapped source of antibiotic potential?

A Frei - Antibiotics, 2020 - mdpi.com
With the widespread rise of antimicrobial resistance, most traditional sources for new drug
compounds have been explored intensively for new classes of antibiotics. Meanwhile, metal …

The potential of organometallic complexes in medicinal chemistry

G Gasser, N Metzler-Nolte - Current opinion in chemical biology, 2012 - Elsevier
Organometallic complexes have unique physico-chemical properties, which have been
widely used in homogenous catalysis, for example, for the synthesis of lead compounds and …

Ferrocene-based drugs, delivery nanomaterials and fenton mechanism: state of the art, recent developments and prospects

C Ornelas, D Astruc - Pharmaceutics, 2023 - mdpi.com
Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …

Small organometallic compounds as antibacterial agents

M Patra, G Gasser, N Metzler-Nolte - Dalton transactions, 2012 - pubs.rsc.org
The emergence of bacterial resistance to commercial antibiotics is an issue of global
importance. During the last two decades, the number of antibacterial agents that have been …

Ferrocene derivatives as anti-infective agents

BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …

Bio‐Organometallic Derivatives of Antibacterial Drugs

MA Sierra, L Casarrubios… - Chemistry–A European …, 2019 - Wiley Online Library
Overuse and misuse of antibacterial drugs has resulted in bacteria resistance and in an
increase in mortality rates due to bacterial infections. Therefore, there is an imperative …

FerriIridium: A Lysosome‐Targeting Iron (III)‐Activated Iridium (III) Prodrug for Chemotherapy in Gastric Cancer Cells

S Kuang, X Liao, X Zhang, TW Rees… - Angewandte …, 2020 - Wiley Online Library
Reported is the FeIII‐activated lysosome‐targeting prodrug FerriIridium for gastric cancer
theranostics. It contains a meta‐imino catechol group that can selectively bond to, and be …