Differential impact of stress and environmental enrichment on corticolimbic circuits

MA Smail, BL Smith, N Nawreen, JP Herman - … biochemistry and behavior, 2020 - Elsevier
Stress exposure can produce profound changes in physiology and behavior that can impair
health and well-being. Of note, stress exposure is linked to anxiety disorders and depression …

Cellular and molecular mechanisms of immunomodulation in the brain through environmental enrichment

G Singhal, EJ Jaehne, F Corrigan… - Frontiers in cellular …, 2014 - frontiersin.org
Recent studies on environmental enrichment (EE) have shown cytokines, cellular immune
components [eg, T lymphocytes, natural killer (NK) cells], and glial cells in causal …

Environmental enrichment alters neurobehavioral development following maternal immune activation in mice offspring with epilepsy

M Zeraati, N Najdi, B Mosaferi, AA Salari - Behavioural brain research, 2021 - Elsevier
Epilepsy is a chronic brain disease affecting millions of people worldwide. Anxiety-related
disorders and cognitive deficits are common in patients with epilepsy. Previous studies have …

The impact of environmental and social factors on learning abilities: a meta‐analysis

CT Lambert, LM Guillette - Biological Reviews, 2021 - Wiley Online Library
Since the 1950s, researchers have examined how differences in the social and asocial
environment affect learning in rats, mice, and, more recently, a variety of other species …

Effects of early adolescent environmental enrichment on cognitive dysfunction, prefrontal cortex development, and inflammatory cytokines after early life stress

CH do Prado, T Narahari, FH Holland… - Developmental …, 2016 - Wiley Online Library
Early postnatal stress such as maternal separation causes cognitive dysfunction later in life,
including working memory deficits that are largely mediated by the prefrontal cortex …

Environmental enrichment enhances cognitive flexibility in C57BL/6 mice on a touchscreen reversal learning task

A Zeleznikow-Johnston, EL Burrows, T Renoir… - …, 2017 - Elsevier
Environmental enrichment (EE) is any positive modification of the 'standard housing'(SH)
conditions in which laboratory animals are typically held, usually involving increased …

Environmental enrichment effects after early stress on behavior and functional brain networks in adult rats

H González-Pardo, JL Arias, G Vallejo, NM Conejo - PloS one, 2019 - journals.plos.org
Early life stress is associated with long-term and pervasive adverse effects on
neuroendocrine development, affecting normal cognitive and emotional development …

Maternal deprivation impairs memory and cognitive flexibility, effect that is avoided by environmental enrichment

J Menezes, BHS das Neves, R Gonçalves… - Behavioural Brain …, 2020 - Elsevier
Maternal deprivation (MD) causes cognitive deficits that persist until adulthood. Thereby, the
environmental enrichment (EE) is widely used to increase brain plasticity. Here, pregnant …

Environmental enrichment decreases anxiety‐like behavior in zebrafish larvae

E Gatto, M Dadda, M Bruzzone… - Developmental …, 2022 - Wiley Online Library
The development of anxiety disorders is often linked to individuals' negative experience. In
many animals, development of anxiety‐like behavior is modeled by manipulating …

Neurobehavioral effects of restricted and unpredictable environmental enrichment in rats

M Rojas-Carvajal, A Sequeira-Cordero… - Frontiers in …, 2020 - frontiersin.org
To study how motivational factors modulate experience-dependent neurobehavioral
plasticity, we modify a protocol of environmental enrichment (EE) in rats. We assumed that …