Genome data have revealed great variation in the numbers of genes in different organisms,
which indicates that there is a fundamental process of genome evolution: the origin of new …

Understanding the phenotypic and molecular mechanisms that contribute to genetic
diversity between and within species is fundamental in studying the evolution of species. In …

Long-read, single-molecule real-time (SMRT) sequencing is routinely used to finish
microbial genomes, but available assembly methods have not scaled well to larger …

Fruit flies of the genus Drosophila have been an attractive and effective genetic model
organism since Thomas Hunt Morgan and colleagues made seminal discoveries with them …

Retrotransposons are highly enriched in the animal genome,–. The activation of
retrotransposons can rewrite host DNA information and fundamentally impact host biology …

High quality reference genomes are crucial to understanding genome function, structure and
evolution. The availability of reference genomes has allowed us to start inferring the role of …

We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200
megabases and contains at least 30,907 genes. The high gene count is a consequence of …

Background Transposable elements are abundant in eukaryotic genomes and it is believed
that they have a significant impact on the evolution of gene and chromosome structure …

We present a fast map**-based algorithm to compute the mappability of each region of a
reference genome up to a specified number of mismatches. Knowing the mappability of a …