The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Late gadolinium enhancement magnetic resonance imaging (LGE MRI) is commonly used
to visualize and quantify left atrial (LA) scars. The position and extent of LA scars provide …

A critical procedure in diagnosing atrial fibrillation is the creation of electro-anatomic
activation maps. Current methods generate these map**s from interpolation using a few …

Abstract Background and Objective: Cardiac electrophysiology is a medical specialty with a
long and rich tradition of computational modeling. Nevertheless, no community standard for …

Abstract Cardiac digital twins (Cardiac Digital Twin (CDT) s) of human electrophysiology
(Electrophysiology (EP)) are digital replicas of patient hearts derived from clinical data that …

Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …

Mathematical models of the human heart are evolving to become a cornerstone of precision
medicine and support clinical decision making by providing a powerful tool to understand …

Background: Current ablation therapy for atrial fibrillation is suboptimal, and long-term
response is challenging to predict. Clinical trials identify bedside properties that provide only …

Cardiac pump function arises from a series of highly orchestrated events across multiple
scales. Computational electromechanics can encode these events in physics-constrained …

The pericardium affects cardiac motion by limiting epicardial displacement normal to the
surface. In computational studies, it is important for the model to replicate realistic motion, as …