Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …

Stroke is the second leading cause of mortality and the major cause of adult physical
disability worldwide. The currently available treatment to recanalize the blood flow in acute …

For a long time, apoptosis was considered the sole form of programmed cell death during
development, homeostasis and disease, whereas necrosis was regarded as an unregulated …

Irrespective of the morphological features of end-stage cell death (that may be apoptotic,
necrotic, autophagic, or mitotic), mitochondrial membrane permeabilization (MMP) is …

Stroke is the second most common cause of death and the leading cause of disability
worldwide. Brain injury following stroke results from a complex series of pathophysiological …

Background and Purpose—Traditionally, cell death after cerebral ischemia was considered
to be exclusively necrotic in nature, but research over the past decade has revealed that …

Oxidative stress in conjunction with glutathione depletion has been linked with various acute
and chronic degenerative disorders, yet the molecular mechanisms have remained unclear …

Stroke is the leading cause of adult disability and mortality in most develo** and
developed countries. The current best practices for patients with acute ischemic stroke …

Cells die by a variety of mechanisms. Terminally differentiated cells such as neurones die in
a variety of disorders, in part, via parthanatos, a process dependent on the activity of poly …